5-Amino-6-[(N-methyl-N-nitroso)amino]-7-methylquinoline

5-Amino-6-[(N-methyl-N-nitroso)amino]-7-methylquinoline, also known as MNMQ, is a chemical compound with the molecular formula C12H12N4O2. It is a synthetic compound and is widely used in various research activities, especially in the field of medicinal chemistry. MNMQ is a yellow crystalline compound that is soluble in organic solvents like ethanol, acetone, and chloroform. It has a melting point of 242-244°C. The compound has a nitroso group (-NO) and an amino group (-NH2) attached to the quinoline ring, which makes it a potent DNA alkylating agent. This means that it can bind to and modify DNA, leading to the inhibition of cell division and ultimately cell death. Due to its chemical properties, MNMQ has been studied for its potential in cancer therapy. It has been found to be effective against various cancer cell lines, including breast cancer, colon cancer, and lung cancer. However, its use in clinical settings is limited due to its toxicity and potential side effects. In addition to its anti-cancer properties, MNMQ has also been studied for its potential in the treatment of parasitic infections, such as malaria and trypanosomiasis. It has shown promising results in preclinical studies, but further research is required before it can be used as a therapeutic agent. Overall, 5-Amino-6-[(N-methyl-N-nitroso)amino]-7-methylquinoline is a potent chemical compound with potential applications in cancer therapy and parasitic infection treatment. However, more studies are needed to fully understand its mechanism of action and potential side effects.