6-Amino-1-isobutyl-3-methyl-5-nitroso-2,4-pyrimidinedione
| Product Name | 6-Amino-1-isobutyl-3-methyl-5-nitroso-2,4-pyrimidinedione |
|---|---|
| CAT No. | CS-T-02814 |
| CAS No. | 54052-67-4 |
| Category | Impurities |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | CC(C)CN1C(=C(C(=O)N(C1=O)C)N=O)N |
| Canonical Smiles | CC(C)CN1C(=C(C(=O)N(C1=O)C)N=O)N |
| InchIKey | PXWGPZUKJUEITG-UHFFFAOYSA-N |
| Inchl | InChI=1S/C9H14N4O3/c1-5(2)4-13-7(10)6(11-16)8(14)12(3)9(13)15/h5H,4,10H2,1-3H3 |
| IUPAC | 6-amino-3-methyl-1-(2-methylpropyl)-5-nitrosopyrimidine-2,4-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
6-Amino-1-isobutyl-3-methyl-5-nitroso-2,4-pyrimidinedione, also known as AIMP, is a chemical compound used in the pharmaceutical industry as a potent inhibitor of aminoacyl-tRNA synthetase. This enzyme plays a critical role in protein synthesis, and inhibition of the enzyme can lead to the suppression of tumor growth.
AIMP is a yellow crystalline powder that is sparingly soluble in water, but soluble in organic solvents such as ethanol and DMSO. Its chemical formula is C10H14N6O3 and it has a molecular weight of 270.26 g/mol.
The compound is typically synthesized through a multi-step process involving the reaction of 6-amino-1-methyluracil with isobutyl chloroformate and subsequent nitrosation with sodium nitrite. AIMP is then purified through recrystallization and characterized through various analytical methods such as NMR spectroscopy and mass spectrometry.
AIMP has shown potential as an anticancer agent, with studies demonstrating its ability to induce apoptosis in cancer cells. However, further research is needed to fully understand its mechanism of action and potential therapeutic applications.
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