Acetophenazine-d4 Dimaleate

Acetophenazine-d4 Dimaleate is a deuterated form of Acetophenazine, which is an antipsychotic medication that acts on the central nervous system. It is commonly used to treat psychotic disorders, such as schizophrenia and bipolar disorder. Acetophenazine-d4 Dimaleate is a salt of Acetophenazine-d4 and maleic acid, which is a dicarboxylic acid. The deuterium labeling of Acetophenazine-d4 Dimaleate makes it useful in pharmacokinetic and pharmacodynamic studies. It is often used as a stable isotope internal standard in mass spectrometry-based analytical methods for drug quantification in biological matrices. Acetophenazine-d4 Dimaleate is administered orally and is rapidly absorbed in the gastrointestinal tract. It reaches peak plasma concentration within 2-4 hours of administration. The drug is metabolized in the liver and excreted in the urine. It has a half-life of approximately 10 hours in adults. The mechanism of action of Acetophenazine-d4 Dimaleate is not fully understood, but it is believed to work by inhibiting the dopamine receptors in the brain. This leads to a reduction in the positive symptoms of psychosis, such as hallucinations and delusions. It is also thought to have some sedative and anticholinergic effects. Like all medications, Acetophenazine-d4 Dimaleate can cause side effects, including drowsiness, dizziness, dry mouth, constipation, and blurred vision. It may also cause extrapyramidal symptoms, such as muscle stiffness, tremors, and tardive dyskinesia. It is important to consult with a healthcare provider before taking any medication.