Amifostine Thiol Dihydrochloride-d4

Product Name Amifostine Thiol Dihydrochloride-d4
Alternate Names Amifostine Stable Isotopes, Stable Isotopes of Amifostine
CAT No. CS-T-93898
CAS No. 14653-77-1 (Unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 211.19 g/mol
Mol. For. C5H12D4Cl2N2S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amifostine
Canonical Smiles C(CN)CNCCS.Cl.Cl
InchIKey XDRLRDHLCIFZIW-UHFFFAOYSA-N
Inchl InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
IUPAC 2-(3-aminopropylamino)ethanethiol;dihydrochloride
Controlled No
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What is the usage and chemical information of Amifostine Thiol Dihydrochloride-d4 ?


Amifostine Thiol Dihydrochloride-d4 is a deuterated analogue of Amifostine Thiol Dihydrochloride, which is an organic compound used in the treatment of cancer. It is a prodrug that is dephosphorylated by alkaline phosphatase to its active form, which acts as a potent cytoprotective agent. This compound is a potent scavenger of reactive oxygen species, which are known to cause cellular damage, and it has been shown to protect normal tissues from the harmful effects of radiation and chemotherapy. Amifostine Thiol Dihydrochloride-d4 is used in various research studies where the use of a deuterated analogue is required. It is a useful tool for pharmacokinetic studies, as it allows the tracking of the compound’s metabolism and distribution in vivo. The deuterated analogue also has a unique mass spectral signature, which can be used to distinguish it from the non-deuterated compound in biological samples. Chemically, Amifostine Thiol Dihydrochloride-d4 is a white crystalline powder with a molecular weight of 248.24 g/mol and a chemical formula of C5H10D4Cl2NOS. It is soluble in water and methanol, and it has a melting point of 245-247°C. This compound is stable under normal conditions of use and storage, and it should be stored in a dry and cool place. It is important to handle this compound with care, as it is a toxic and irritant substance.

Related Compounds

Amifostine Thiol-13C3 Dihydrochloride |

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