Anacetrapib 13C6

Anacetrapib 13C6 is a stable isotope-labeled version of the drug Anacetrapib. Anacetrapib is a drug used to treat high cholesterol levels in the blood. It belongs to the class of drugs known as CETP inhibitors. CETP inhibitors work by inhibiting the activity of the cholesteryl ester transfer protein (CETP), which is responsible for transferring cholesterol esters from high-density lipoprotein (HDL) to low-density lipoprotein (LDL) particles. By inhibiting CETP activity, Anacetrapib increases the number of HDL particles in the blood and decreases the number of LDL particles, which leads to a decrease in the overall level of cholesterol in the blood. Anacetrapib 13C6 is used as a research tool to study the pharmacokinetics and metabolism of Anacetrapib in the body. It is labeled with six carbon-13 atoms, which allows researchers to track the drug's movement and transformation in the body using mass spectrometry. This information can be used to optimize the dosing and design of Anacetrapib and other CETP inhibitors to improve their efficacy and reduce their side effects. Chemically, Anacetrapib 13C6 is a white to off-white powder with a molecular formula of C34H38D6F2N4O5S2. Its molecular weight is 712.89 g/mol. It is soluble in dimethyl sulfoxide and slightly soluble in water. Anacetrapib 13C6 should be stored at -20°C and protected from light. It is intended for research purposes only and is not approved for human or veterinary use.