Apixaban Amino Acid Impurity

Product Name Apixaban Amino Acid Impurity
Alternate Names Apixaban Impurities, Impurities of Apixaban
CAT No. CS-EO-00222
CAS No. 2206825-87-6
Category Impurities
Stock IN-Stock
Mol. Wt. 477.51 g/mol
Mol. For. C₂₅H₂₇N₅O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Apixaban
Smileys O=C(O)CCCCNC1=CC=C(N2CCC3=C(N(C4=CC=C(OC)C=C4)N=C3C(N)=O)C2=O)C=C1
Canonical Smiles COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)NCCCCC(=O)O)C(=N2)C(=O)N
InchIKey JYXZVSMVCZWUPI-UHFFFAOYSA-N
Inchl InChI=1S/C25H27N5O5/c1-35-19-11-9-18(10-12-19)30-23-20(22(28-30)24(26)33)13-15-29(25(23)34)17-7-5-16(6-8-17)27-14-3-2-4-21(31)32/h5-12,27H,2-4,13-15H2,1H3,(H2,26,33)(H,31,32)
IUPAC 5-[4-[3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridin-6-yl]anilino]pentanoic acid
Controlled No
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Apixaban is a novel oral anticoagulant that works by inhibiting Factor Xa, a crucial enzyme in the coagulation cascade. It is used to prevent or treat blood clots in patients with atrial fibrillation, deep vein thrombosis, and pulmonary embolism. However, during the synthesis of Apixaban, small amounts of impurities can be formed. One of these impurities is the Apixaban Amino Acid Impurity. The Apixaban Amino Acid Impurity is a by-product of the synthesis process that occurs during the formation of Apixaban. This impurity is a small molecule that contains an amino acid residue that is not present in the Apixaban molecule. The impurity is formed due to a side reaction that occurs during the synthesis process. The Apixaban Amino Acid Impurity is usually present in very small amounts and is not harmful to humans. However, it is important to monitor the levels of this impurity to ensure that it does not accumulate to harmful levels. The impurity can be removed from the final product through various purification methods. In conclusion, the Apixaban Amino Acid Impurity is an impurity that can be formed during the synthesis of Apixaban. While it is not harmful to humans, it is important to monitor its levels to ensure that it does not accumulate to harmful levels. The impurity can be removed from the final product through various purification methods.

Related Compounds

Apixaban methyl ester Dimer imp | N-(4-methoxyphenyl)nitrous hydrazide | Apixaban Impurity 39 | Apixaban Related Compound 5 | Apixaban imp Dimer-2 | N-Nitroso 5-Chloropentanamide Apixaban | O-Desmethyl Apixaban | Apixaban Impurity - (2 H2O) | Apixaban Related Compound D | Apixaban impurity B | Apixaban Impurity 29 | Apixaban Related Compound 1 | Apixaban Impurity 26 | Apixaban Impurity 43 | N-Nitroso Apixaban Amino Acid Impurity | Apixaban carboxybutylaminophenyl | Apixaban impurity E | Apixaban Chloro Impurity | Apixaban Amino Acid Impurity Hydrochloride | Apixaban Impurity 34 | ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate | Apixaban Ester Impurity | Apixaban Impurity 28 | Apixaban Hydroxy acid Impurity | Apixaban Impurity C | Ethyl (2E)-2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetate | Apixaban PG Ester-I | Apixaban Impurity 32 | Apixaban Ethoxy Diethylamide impurity | Apixaban Nitrosoacid impurity | Ethyl-2-chloro-2-(2-(4-hydroxy phenyl)hydrazono)acetate | Ethyl 2-chloro-2-[2-(2-methoxyphenyl)hydrazin-1-ylidene]acetate | Apixaban Impurity 16 | Apixaban Impurity 5 | Apixaban Impurity 3 | Apixaban Impurity - (3/2 H2O) | Apixaban Impurity 13 Potassium Salt | Apixaban Impurity 51 | Apixaban Impurity 33 | Apixaban Impurity 24 | Apixaban Related Compound H | Apixaban Impurity 14 | Apixaban impurity A | Apixaban Impurity 38 | Apixaban Related Compound G | Apixaban Impurity 12 | Apixaban Impurity 17 | Apixaban Impurity 84 | Desmethoxy Apixaban | Apixaban Methyl ester Impurity | Apixaban diacid impurity | Apixaban Nitrosoamide impurity | Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate | Apixaban Impurity 27 | Apixaban PG Ester-II | Hydroxy O-Demethyl Apixaban | Apixaban Impurity 40 | AXN-III | O-Desmethyl Apixaban Sulfate | Apixaban Impurity 44 | Apixaban Impurity 3 | Apixaban impurity D | Apixaban Impurity 52 | Apixaban dimer impurity | Apixaban Isopropyl Ester Impurity |

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