Aripiprazole (D8)

Aripiprazole (D8) is a deuterated form of the atypical antipsychotic drug aripiprazole. It is used to treat various mental illnesses including schizophrenia, bipolar disorder, and major depressive disorder. Aripiprazole (D8) works by balancing the levels of certain chemicals in the brain, particularly dopamine and serotonin, which are responsible for regulating mood, behavior, and cognition. Chemically, aripiprazole (D8) is a quinolinone derivative with a molecular weight of 448.6 g/mol. It has a chemical formula of C23H27D8ClN4O2 and is a white to yellow crystalline powder that is practically insoluble in water. Aripiprazole (D8) is typically administered orally as tablets or as an injection. The drug has a half-life of approximately 75 hours and is metabolized primarily in the liver by the cytochrome P450 enzyme system. It is excreted in the urine and feces, with less than 1% of the drug being excreted unchanged in the urine. Like other antipsychotic medications, aripiprazole (D8) can cause side effects such as weight gain, drowsiness, and tremors. It is important for patients to discuss any potential side effects with their healthcare provider to ensure that the benefits of the medication outweigh the risks. Additionally, aripiprazole (D8) should not be stopped abruptly without consulting a healthcare provider, as it can lead to withdrawal symptoms.