Azacytidine 13C5
| Product Name | Azacytidine 13C5 |
|---|---|
| Alternate Names | Cytidine Stable Isotopes, Stable Isotopes of Cytidine |
| CAT No. | CS-O-03615 |
| CAS No. | 320-67-2(Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 249.17 g/mol |
| Mol. For. | C8H12N4O5 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Cytidine |
| Smileys | O[13C@H]1[13C@H](N(C=NC(N)=N2)[13C]2=O)O[13C@H](CO)[13C@H]1O |
| Canonical Smiles | C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N |
| InchIKey | NMUSYJAQQFHJEW-KVTDHHQDSA-N |
| Inchl | InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1 |
| IUPAC | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Azacytidine 13C5 is a stable isotopic labeled version of the chemical compound Azacytidine. Azacytidine is a nucleoside analogue that is used in cancer treatment, specifically for the treatment of myelodysplastic syndrome (MDS). It works by inhibiting DNA methyltransferases, which are enzymes that add methyl groups to DNA, leading to the silencing of certain genes. By inhibiting this process, Azacytidine can reactivate silenced genes, restoring normal gene function.
Azacytidine 13C5 is used in metabolic studies and pharmacokinetic research to trace the bioavailability and metabolism of Azacytidine in vivo. It is also used in the analysis of Azacytidine in biological samples by mass spectrometry. Since it is a stable isotope, it does not undergo decay and can be used as a tracer to track the fate of Azacytidine in the body.
Chemically, Azacytidine 13C5 is a nucleoside analogue that is structurally similar to cytidine, a natural component of RNA. It differs from cytidine by the presence of an azide group at the 5-position of the pyrimidine ring. The 13C5 label refers to the presence of five carbon atoms in the molecule that have been replaced with the stable isotope carbon-13. This labeling does not alter the biological activity of Azacytidine but allows for precise tracking of the compound in biological systems.
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Related Compounds
CYTIDINE 5-MONOPHOSPHATE 15N3 | Beta-d-N4-Hydroxycytidine - D2 | CYTIDINE RIBOSE-2-13C | N4-Hydroxycytidine 13C,15N2 | Cytidine-1’-13C | CYTIDINE RIBOSE-13C5 | CYTIDINE RIBOSE-5,5-D2 |