Azasetron-d3 Hydrochloride

Product Name Azasetron-d3 Hydrochloride
CAT No. CS-T-48457
CAS No. 1216505-58-6
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Therapeutic Anti-Emetics
Smileys O=C(C1=C(OCC(N2C([2H])([2H])[2H])=O)C2=CC(Cl)=C1)NC3CN4CCC3CC4.[H]Cl
Canonical Smiles CN1C(=O)COC2=C(C=C(C=C21)Cl)C(=O)NC3CN4CCC3CC4.Cl
InchIKey DBMKBKPJYAHLQP-NIIDSAIPSA-N
Inchl InChI=1S/C17H20ClN3O3.ClH/c1-20-14-7-11(18)6-12(16(14)24-9-15(20)22)17(23)19-13-8-21-4-2-10(13)3-5-21;/h6-7,10,13H,2-5,8-9H2,1H3,(H,19,23);1H/i1D3;
IUPAC N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-3-oxo-4-(trideuteriomethyl)-1,4-benzoxazine-8-carboxamide;hydrochloride
Controlled No
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Azasetron-d3 Hydrochloride is a deuterated version of Azasetron Hydrochloride, which is a highly potent and selective serotonin 5-HT3 receptor antagonist. Azasetron-d3 Hydrochloride is used as an antiemetic drug to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It is also used for the management of motion sickness and postoperative nausea and vomiting. Azasetron-d3 Hydrochloride works by blocking the action of serotonin, which is a neurotransmitter involved in the regulation of vomiting reflexes. This drug binds to the 5-HT3 receptors in the gastrointestinal tract and central nervous system, preventing the activation of vomiting centers in the brain. The chemical formula of Azasetron-d3 Hydrochloride is C16H20D3ClN4O2, and its molecular weight is 330.8 g/mol. The drug is a white to off-white powder, and it is soluble in water and methanol. Azasetron-d3 Hydrochloride is stable under normal storage conditions, and it should be stored in a cool, dry place away from light and moisture. The recommended dosage of Azasetron-d3 Hydrochloride depends on the age, weight, and medical condition of the patient. It is usually administered orally, as a tablet or a solution, and it can also be given intravenously. The drug is generally well-tolerated, with few side effects, such as headache, dizziness, constipation, and diarrhea. However, Azasetron-d3 Hydrochloride should not be used in patients with a known hypersensitivity to the drug or in combination with certain medications, such as apomorphine or tricyclic antidepressants.

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