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D-Glucose-1,6 13C2-6-C-d2, also known as labeled glucose, is a stable isotope-labeled compound used in various fields such as metabolic research, drug development and clinical diagnostics. It is a modified form of glucose, where two carbon atoms in position 13 and 6 are replaced with stable isotopes, carbon-13 and deuterium, respectively. This labeling enables researchers to track the metabolic pathways of glucose in the body or in vitro experiments.
In metabolic research, labeled glucose is used to study glucose metabolism in cells, tissues and organisms. By administering labeled glucose, researchers can trace the fate of glucose in the body and measure various metabolic parameters such as glucose uptake, glycolysis, glycogen synthesis and glucose oxidation. This information is vital in understanding the underlying mechanisms of metabolic disorders such as diabetes and obesity.
In drug development, labeled glucose is used to study the pharmacokinetics and pharmacodynamics of glucose-lowering drugs. By administering labeled glucose, researchers can measure the effect of drugs on glucose metabolism and monitor the drug's efficacy and safety.
In clinical diagnostics, labeled glucose is used as a tracer in various imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI). By labeling glucose with a radioactive isotope such as fluorine-18, researchers can visualize the uptake and distribution of glucose in tissues and organs, which is useful in diagnosing and monitoring various diseases such as cancer and Alzheimer's disease.
In summary, D-Glucose-1,6 13C2-6-C-d2 is a versatile compound used in various fields for studying glucose metabolism, drug development and clinical diagnostics. Its stable isotope labeling enables researchers to trace the fate of glucose in the body and measure various metabolic parameters, leading to a better understanding of metabolic disorders and the development of effective treatments.
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