Enalaprilat-d5 (phenyl-d5)
| Product Name | Enalaprilat-d5 (phenyl-d5) |
|---|---|
| Alternate Names | Enalapril Stable Isotopes, Stable Isotopes of Enalapril |
| CAT No. | CS-O-03157 |
| CAS No. | 349554-00-3 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 353.43 g/mol |
| Mol. For. | C₁₈H₁₉D₅N₂O₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Enalapril |
| Purity | 95% |
| Therapeutic | Anti-Hypertensives |
| Smileys | CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
| Canonical Smiles | CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
| InchIKey | LZFZMUMEGBBDTC-CHNCPRCNSA-N |
| Inchl | InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14+,15-/m0/s1/i2D,3D,4D,6D,7D |
| IUPAC | (2S)-1-[(2S)-2-[[(1R)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Enalaprilat-d5 (phenyl-d5) is a deuterated form of Enalaprilat, which is a medication used to treat hypertension, heart failure, and diabetic kidney disease. Enalaprilat is a prodrug that is converted to its active form, Enalaprilat, in the liver. Enalaprilat-d5 (phenyl-d5) is chemically identical to Enalaprilat but has five deuterium atoms in the phenyl group, which makes it useful in pharmacokinetic studies and drug metabolism research.
Enalaprilat-d5 (phenyl-d5) can be administered intravenously to patients who cannot take oral medication. The medication works by inhibiting the angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor that raises blood pressure. By inhibiting ACE, Enalaprilat-d5 (phenyl-d5) reduces the levels of angiotensin II, resulting in vasodilation and lowered blood pressure.
Enalaprilat-d5 (phenyl-d5) has a half-life of approximately 1.3 hours and is eliminated primarily through renal excretion. The deuterium labeling on the phenyl group does not affect the pharmacological properties of Enalaprilat-d5 (phenyl-d5), but it does allow for accurate measurements of drug levels in the body and the study of drug metabolism.
Overall, Enalaprilat-d5 (phenyl-d5) is a useful tool in pharmacokinetic and drug metabolism research. Its chemical properties and pharmacological effects make it an effective medication for treating hypertension and heart failure.
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Related Compounds
Enalaprilat D5 Sodium Salt | Enalapril D5 | Enalaprilat D5 maleate | Enalapril D5 maleate | Enalapril-d5 tert-Butyl Ester | Enalapril-d3 |