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Flufenazin D8 is a deuterated derivative of the antipsychotic drug fluphenazine, which is commonly used to manage symptoms of schizophrenia and other psychotic disorders. Flufenazin D8 is a stable isotopically labeled compound, containing eight deuterium atoms, which makes it useful for quantitative analysis of fluphenazine metabolites in biological samples using mass spectrometry.
Flufenazin D8 is primarily used in pharmacokinetic studies to investigate the metabolism, distribution, and elimination of fluphenazine in the body. It is also employed in drug-drug interaction studies to determine the effects of other medications on the metabolism of fluphenazine.
The molecular formula of Flufenazin D8 is C22H24D8F3N3OS, and it has a molecular weight of 450.62 g/mol. Its chemical structure is similar to that of fluphenazine, with the addition of eight deuterium atoms. Flufenazin D8 is a white to off-white powder that is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.
While Flufenazin D8 is not intended for human or veterinary use, it plays a crucial role in preclinical drug development and research. Its stable isotopic labeling allows for accurate measurement of drug levels in biological samples, which can aid in the development of safer and more effective antipsychotic medications.
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