Leukotriene E4 13C3,15N

[13C3,15N]-Leukotriene E4 is a labeled form of Leukotriene E4 (LTE4), which is a potent inflammatory mediator produced in response to various stimuli such as allergens, infections, and toxins. The labeled version is used in medical research to study the metabolic pathways and mechanisms of action of LTE4 in vivo. The labeling of [13C3,15N]-Leukotriene E4 involves the incorporation of carbon-13 and nitrogen-15 isotopes into the molecule. This allows researchers to track the labeled molecule using mass spectrometry and other techniques, providing valuable insights into the biological processes and interactions involving LTE4. In terms of usage, [13C3,15N]-Leukotriene E4 is commonly employed in pharmacological and clinical studies to investigate the role of LTE4 in various disease states, including asthma, allergic rhinitis, and inflammatory bowel disease. Researchers can use the labeled molecule to monitor the metabolism and clearance of LTE4 in vivo, as well as to identify potential drug targets and therapeutic interventions. Overall, [13C3,15N]-Leukotriene E4 is a valuable tool for investigating the complex biological pathways and interactions involved in inflammation and related diseases. Its use in medical research has the potential to lead to new treatments and improved outcomes for patients.