Losartan Azide impurity

Product Name Losartan Azide impurity
Alternate Names Losartan Impurities, Impurities of Losartan
CAT No. CS-O-35717
CAS No. 727718-93-6
Category Impurities
Stock IN-Stock
Mol. Wt. 447.92 g/mol
Mol. For. C₂₂H₂₂ClN₉
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Losartan
Smileys ClC1=C(CN=[N+]=[N-])N(CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C(CCCC)=N1
Controlled No
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Losartan Azide is an impurity that is commonly found in Losartan potassium, a medication used to treat high blood pressure. The compound is a derivative of the parent compound Losartan and is formed as a result of the incomplete reaction between Losartan and sodium azide. Losartan Azide impurity is a white or off-white crystalline powder that is slightly soluble in water and organic solvents such as methanol, ethanol, and acetone. It has a molecular weight of 452.5 g/mol and a chemical formula of C22H22ClKN6O. While Losartan Azide impurity itself does not have any therapeutic benefits, it is important to monitor its levels in Losartan potassium as it can potentially cause toxicity and adverse effects. Therefore, it is essential to minimize the levels of this impurity during the manufacturing process of Losartan potassium to ensure its safety and efficacy. In conclusion, Losartan Azide impurity is an unwanted by-product that can be formed during the synthesis of Losartan potassium. It is important to monitor and control its levels in Losartan potassium to ensure therapeutic efficacy and safety for patients with high blood pressure.

Related Compounds

Losartan a-Butyl-losartan Aldehyde Adduct | Losartan Impurity 15 | Losartan Potassium EP Impurity J | Losartan Related Compound E | Losartan Impurity 5 | Losartan Acetyloxy N1-Trityl Impurity | Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde | Losartan Acetyloxy Impurity | Losartan Imidazo[1,5-b]isoquinoline Impurity | N-Trityl Losartan Carboxylic Acid | Losartan EP Impurity L | Losartan Impurity 1 | Losartan Potassium EP Impurity K | Losartan EP Impurity M | Losartan Potassium EP Impurity C | N-Trityl Losartan Carboxaldehyde | Losartan Potassium EP Impurity H | Losartan isocyano Impurity | Losartan Impurity 6 | Losartan Hydroxy N1-Trityl Impurity | Nitroso Losartan | Losartan EP Impurity F | Losartan Related Compound D | Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan | Losartan N1-Trityl Impurity | Losartan Impurity 7 | Losartan EP Impurity B | Losartan EP Impurity C | Losartan Impurity 29 | Losartan Dimer Azide | Losartan Impurity 8 | Losartan Amine | Losartan Potassium EP Impurity A | N-Trityl Losartan Isomer | Losartan Potassium EP Impurity E |

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