N-nitrosamine bumetanide [Mixture of isomers]

Product Name N-nitrosamine bumetanide [Mixture of isomers]
Alternate Names Bumetanide Impurities, Impurities of Bumetanide
CAT No. CS-P-08514
CAS No. 2490432-02-3
Category Impurities
Stock IN-Stock
Mol. Wt. 393.41 g/mol
Mol. For. C₁₇H₁₉N₃O₆S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Bumetanide
Controlled No
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N-nitrosamine bumetanide is a mixture of isomers that belongs to the class of diuretic drugs. This drug is commonly used to treat conditions such as edema and hypertension. It works by inhibiting the reabsorption of sodium and chloride ions in the kidneys, which results in an increase in the excretion of water and electrolytes from the body. However, the use of N-nitrosamine bumetanide is not without risks. The chemical structure of this drug contains a nitrosamine group, which is known to be carcinogenic. Studies have shown that exposure to nitrosamines can lead to the development of cancer in humans. Therefore, the use of N-nitrosamine bumetanide should be carefully monitored, and the dose should be kept as low as possible. Chemically, N-nitrosamine bumetanide is a yellowish-white powder that is soluble in water and ethanol. It has a molecular weight of 364.4 g/mol and a melting point of 202-204°C. The drug is stable under normal conditions of use and storage, but it should be protected from light and moisture. In conclusion, N-nitrosamine bumetanide is a diuretic drug that is effective in treating edema and hypertension. However, its use should be carefully monitored due to its potential carcinogenic properties.

Related Compounds

Bumetanide Butyl Ester | Bumetanide Lactose Adduct Impurity | Bumetanide EP impurity B | Bumetanide lactose adduct impurity acetate salt | N-Desbutyl-N-propyl Bumetanide | Bumetanide EP impurity D | Bumetanide impurity 2 | Bumetanide EP Impurity A |

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