N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid

Also known as: - Nitrosamine Impurities or nitrosamine impurities of -
Product Name N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid
Alternate Names - Stable Isotopes, Stable Isotopes of -
CAT No. CS-T-94540
CAS No. 30248-47-6 (Unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 135.13 g/mol
Mol. For. C4HD5N2O3
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API -
Controlled No
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N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid (d5-NO-ACA) is a stable isotopically labeled derivative of N-Nitroso-L-(azetidine-2-carboxylic acid), which is a potent carcinogenic agent. d5-NO-ACA is used as an internal standard for analyzing NO-ACA in biological samples. This compound is used in the study of the mechanism of nitrosation and carcinogenicity of NO-ACA. The labeled compound is useful for quantitative analysis of NO-ACA in biological samples such as urine and blood. NO-ACA is a potent carcinogen that has been shown to induce tumors in animal models. This compound is formed by the reaction of nitrite with the amino acid proline. NO-ACA is believed to be involved in the formation of nitrosamines, which are known to be carcinogenic. The mechanism of action of NO-ACA is not well understood, but it is believed to be involved in the production of DNA adducts and the inhibition of DNA repair mechanisms. The chemical formula of d5-NO-ACA is C5H4D5N3O3. It has a molecular weight of 176.15 g/mol. The compound has a melting point of 203-205°C and a boiling point of 446.5°C. d5-NO-ACA is soluble in water and ethanol. The compound should be stored at -20°C and protected from light. It is important to handle the compound with caution as it is a potential carcinogen.

Related Compounds

rac-Hesperetin 7-O-Sulfate Sodium Salt-d3 | Clofarabine-13C1, 15N3 | SN-38 Glucuronide-13C3 | Atropine-D3 Hydrochloride | N-(tert-butyl-D9)-5,6-diphenylpiperazin-2-amine | N-Fmoc-D-phenylalanine-d5 | HT2-13C22 | Esaxerenone-d4 | Bis(tosyloxy)methane-D₂ | Mono(2,3-dibromopropyl-d5) Phosphate Biscyclohexylamine Salt | Dibutyl L-Tartrate-D18 | N-Methyldiethanolamine-d3 Hydrochloride | Azapetine-d4 Hydrochloride | N-Nitroso Morpholine-D8 (1000µg/mL) in Methanol | AEE 788-d5 | Chlorotoluron-13C6 | Ethyl 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoate-d3 | N-Fmoc-L-serine-13C3,15N | Rebaudioside B (13CD2) | QX 314 Bromide-d5 | Deschloro-(S)-efavirenz-d4 | N-Nitrosobis(2-hydroxypropyl)amine-d12 | Rebaudioside D (13CD2) | Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine-d4 | cis-Vaccenic acid-13C4 | Serotonin-13C215N Hydrochloride | Sulfaethoxypyridazine-d7 (major) | DEHYDROEPIANDROSTERONE-d5 SOLUTION (DHEA-D5) AMPOLA 100 μG/ML | Vadadustat-13C2,D2,15N | N-Iodoacetyltyramine-d4 | Gamma-Hydroxybutyric acid glucuronide-d6 | Saroglitazar-d5 | Di(n-butyl-d9) 1,10-Decanedioate | N1-Acetyl Triethylenetetramine D4 | Descarboxyl Febuxostat-d9 | Ethyl α-Ketoisocaproate-d7 | Clindamycin B-d3 2-Phosphate | Diethyl Itaconate-13C5 | Vardenafil Oxopiperazine-D6 (Impurity) | Trityl Olmesartan-d6 Medoxomil | O-2-Amino-2-methylpropyl Bilastine-d6 | BAR505-d5 | N-[1-(3’-Benzyloxyphenyl)ethyl]-N-(methyl-d3)-O-ethylcarbamate | Boc-N-(methyl-d3)-L-alanine-d4 | Benzaldehyde-2-d, 4,5-dihydroxy | Huperzine A HCl -d4 | N,N’-Di-Boc-O-di-tert-butyl Pentosidine-d3 | Cirazoline-d4 Hydrochloride | Nor Mianserin-d6 (Major) | Trimellitic Acid -13C3 | C-α-NAC Trimethoprim-d3 | Glycinexylidide-​d6 | Tetraethylene Glycol-d8 | Ethyl (2R,3R,4E)-2-Amino-3-hydroxy-4-octadecenoate-13C2 | Phenoxypropazine-d5 | Morphine 3-b-D-Glucuronide-D6 | Itaconic Acid-13C5,d4 | Salicylic Acid 2-O-b-D-Glucoside-D4 | Indole-2,4,5,6,7-d5 | Pralidoxime Iodide-d3 (2-PAM-d3) | ICI 118551-d7 Hydrochloride | ZK 159222-d4 | rac 10-Hydroxy-1-undecen-6-one-d6 | a,a-Diphenyl-1-azabicyclo[2.2.2]octane-4-methanol-d10 | BGJ 398-D5 | NSC 521542 -13C4 | Carbovir-13C,d2 Triphosphate Triethylamine Salt | Defluoro Hydroxy AM-694-d4 | Oxybenzone-(phenyl-13C6) | rac-Metalaxyl Carboxylic Acid-d6 |

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