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N-Nitroso-N-methyl-N-dodecylamine-d5, also known as NDMA-d5, is a deuterated form of N-Nitroso-N-methyl-N-dodecylamine. It is a stable isotope-labeled compound that is commonly used in research and analytical applications. NDMA-d5 is a synthetic organic compound that is typically used as a standard or internal standard in gas chromatography-mass spectrometry (GC-MS) analyses.
NDMA-d5 is a highly reactive compound and is classified as a potent carcinogen. It is formed through the reaction of nitrite and secondary amines, such as N-methyl-N-dodecylamine. NDMA-d5 is commonly found in tobacco smoke, cured meats, and certain water supplies, and is a known environmental contaminant.
In analytical chemistry, NDMA-d5 is often used as an internal standard to accurately quantify the concentration of NDMA in samples. This is particularly important in the detection of NDMA in drinking water, where it is considered a significant public health concern. The deuterated form of NDMA is preferred as an internal standard due to its stable isotopic composition, which allows for accurate measurement without interference from other compounds.
Overall, NDMA-d5 is an important analytical tool in the detection and quantification of NDMA, a known carcinogen and environmental contaminant.
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