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N-Nitrosoethylmethylamine-d3 (N-Nitroso-d3-EMEA) is a deuterated derivative of N-Nitrosoethylmethylamine (N-Nitroso-EMEA), a potent carcinogen and mutagen. N-Nitroso-d3-EMEA is a stable isotopic labeled compound, used in research studies for the detection, quantification, and identification of N-Nitroso-EMEA in biological samples.
N-Nitroso-EMEA is formed through the reaction of nitrosating agents with secondary amines, and it has been detected in various food products, including beer, cheese, and bacon. It is also a byproduct of certain industrial processes, such as rubber manufacturing and pesticide production. The compound is known to cause DNA damage, which can lead to the development of cancer.
N-Nitroso-d3-EMEA is used as a reference standard in analytical chemistry for the accurate measurement of N-Nitroso-EMEA in biological samples. Its chemical properties and structure are similar to N-Nitroso-EMEA, except for the presence of three deuterium atoms in the molecule. This isotopic labeling makes it possible to distinguish N-Nitroso-d3-EMEA from N-Nitroso-EMEA in complex biological matrices, such as blood or urine.
In conclusion, N-Nitroso-d3-EMEA is an important tool for researchers studying the carcinogenic and mutagenic properties of N-Nitroso-EMEA. Its isotopic labeling allows for accurate detection and quantification of N-Nitroso-EMEA in biological samples, which is crucial for assessing the potential health risks associated with exposure to this carcinogen.
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