Nitrosobis(2-hydroxyethyl)amine

Product Name Nitrosobis(2-hydroxyethyl)amine
CAT No. CS-T-37198
CAS No. 1116-54-7
Category Impurities
Stock IN-Stock
Mol. Wt. 134.13 g/mol
Mol. For. C4H10N2O3
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys OCCN(N=O)CCO
Canonical Smiles C(CO)N(CCO)N=O
InchIKey YFCDLVPYFMHRQZ-UHFFFAOYSA-N
Inchl InChI=1S/C4H10N2O3/c7-3-1-6(5-9)2-4-8/h7-8H,1-4H2
IUPAC N,N-bis(2-hydroxyethyl)nitrous amide
Controlled No
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Nitrosobis(2-hydroxyethyl)amine, also known as N-nitroso-N-(2-hydroxyethyl)amine or NHEA, is a synthetic compound that is commonly used in research studies as a carcinogenic agent. It is a clear, yellowish liquid that has a strong odor and is highly soluble in water. In experimental settings, NHEA is often used to induce tumors in laboratory animals, particularly in studies that examine the mechanisms of carcinogenesis. It is believed that NHEA acts by inducing DNA damage and oxidative stress, which can lead to the formation of cancerous cells. Despite its use in research, NHEA is not commonly used in industrial or commercial applications due to its toxicity and potential health risks. Exposure to NHEA has been linked to an increased risk of cancer, particularly of the bladder and liver. In terms of chemical structure, NHEA is a nitrosamine compound that contains a nitroso functional group (-NO) attached to a secondary amine. It also contains two hydroxyethyl groups (-CH2CH2OH) that are attached to the nitrogen atom of the secondary amine. Overall, NHEA is a potent carcinogen that is commonly used in research settings to induce tumors and study the mechanisms of carcinogenesis. However, its potential health risks and toxicity limit its use in industrial and commercial applications.

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