Nitrosobis(2-hydroxyethyl)amine-d8

Also known as: Amine, Nitroso Nitrosamine Impurities or nitrosamine impurities of Amine, Nitroso
Product Name Nitrosobis(2-hydroxyethyl)amine-d8
Alternate Names Amine, Nitroso Stable Isotopes, Stable Isotopes of Amine, Nitroso
CAT No. CS-T-83802
CAS No. 1173019-53-8
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 142.18 g/mol
Mol. For. C4H2D8N2O3
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amine, Nitroso
Purity Not less than 99.8%
Smileys C(CO)N(CCO)N=O
Canonical Smiles C(CO)N(CCO)N=O
InchIKey YFCDLVPYFMHRQZ-SVYQBANQSA-N
Inchl InChI=1S/C4H10N2O3/c7-3-1-6(5-9)2-4-8/h7-8H,1-4H2/i1D2,2D2,3D2,4D2
IUPAC N,N-bis(1,1,2,2-tetradeuterio-2-hydroxyethyl)nitrous amide
Controlled No
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Nitrosobis(2-hydroxyethyl)amine-d8 is a deuterated analog of Nitrosobis(2-hydroxyethyl)amine (NOC-9), a potent nitric oxide (NO) donor. Nitric oxide is a small molecule that plays a critical role in various physiological and pathological processes such as vasodilation, neurotransmission, immune response, and inflammation. NOC-9 is widely used in research to study the biological effects of NO in vitro and in vivo. The deuterated form, Nitrosobis(2-hydroxyethyl)amine-d8, is chemically identical to NOC-9 but with eight deuterium atoms replacing eight hydrogen atoms. This modification makes it useful in mass spectrometry-based studies to differentiate between the labeled and unlabeled forms of NOC-9 and to determine the pharmacokinetics and metabolism of NOC-9 in vivo. Nitrosobis(2-hydroxyethyl)amine-d8 can be synthesized by the reaction of deuterated hydroxylamine with diethanolamine followed by oxidation with sodium nitrite. It has a molecular weight of 191.28 g/mol and a chemical formula of C4H13D8N2O2. Its physical and chemical properties are similar to those of NOC-9, including its ability to release NO in a concentration-dependent manner. In conclusion, Nitrosobis(2-hydroxyethyl)amine-d8 is a valuable tool for researchers investigating the biological effects of NOC-9 and nitric oxide. Its deuterated form allows for precise measurement and quantification in mass spectrometry-based experiments.

Related Compounds

N-nitrosodiethylamine D5 _1mg_1ml in methanol (mixture of isomers) |

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