nPOC-POC Tenofovir
| Product Name | nPOC-POC Tenofovir |
|---|---|
| Alternate Names | Tenofovir Impurities, Impurities of Tenofovir |
| CAT No. | CS-O-10862 |
| CAS No. | 1217542-13-6 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 519.44 g/mol |
| Mol. For. | C₁₉H₃₀N₅O₁₀P |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Tenofovir |
| Purity | 99.39 |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | CCCOC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OC(C)C |
| Canonical Smiles | CCCOC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OC(C)C |
| InchIKey | FSHYLBFEGOTZGO-OAMPWVDCSA-N |
| Inchl | InChI=1S/C19H30N5O10P/c1-5-6-28-18(25)29-10-32-35(27,33-11-30-19(26)34-13(2)3)12-31-14(4)7-24-9-23-15-16(20)21-8-22-17(15)24/h8-9,13-14H,5-7,10-12H2,1-4H3,(H2,20,21,22)/t14-,35?/m1/s1 |
| IUPAC | [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propyl carbonate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
nPOC-POC Tenofovir is a novel prodrug of Tenofovir, which is an antiviral drug used for the treatment of HIV and hepatitis B. nPOC-POC Tenofovir is designed to improve the pharmacokinetics and bioavailability of the parent drug by increasing its solubility and stability in the body. The prodrug is rapidly converted to Tenofovir in the body, which then inhibits the reverse transcriptase enzyme of the virus, preventing the replication of the virus and slowing down the progression of the disease.
The chemical structure of nPOC-POC Tenofovir consists of two prodrug moieties, nPOC and POC, attached to the parent drug Tenofovir. These moieties improve the physicochemical properties of the drug by enhancing its water solubility and lipophilicity. The prodrug is metabolized by esterases in the body, releasing Tenofovir, which is then converted to its active form, Tenofovir diphosphate, inside the cells.
The usage of nPOC-POC Tenofovir is similar to that of Tenofovir, and it is administered orally as a tablet. The recommended dosage is 300 mg once daily for adults, and it is usually taken with food. The prodrug has been shown to be well-tolerated and safe in clinical trials, with no significant adverse effects reported. Its improved pharmacokinetic properties make it a promising candidate for the treatment of HIV and hepatitis B, especially in resource-limited settings where the availability of drugs with better bioavailability is limited.
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Related Compounds
Tenofovir Related Compound 5 | TAF SRS diastereomer | Mono ester impurity (Tenofovir) | Tenofovir Impurity 62 | Tenofovir Mixed dimer | Tenofovir alafenamide (RRS) diasteroisomer | Tenofovir Diphenyl HemiFumarate salt | Tenofovir DP-IV | Tenofovir Impurity 35 | TAF Propyl ester Impurity | tenofovir related impurity | Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers) | Desmethyl Tenofovir Disoproxil Fumarate | Tenofovir Disoproxil Dimer | Tenofovir Alafenamide Racemic D Isomer | Tenofovir Alafenamide (RSR) Diasteroisomer | Tenofovir diphosphate | Isopropyl Tenofovir | Tenofovir Disoproxil T5 Impurity | Tenofovir Alafenamide Enantiomer | Mono-POC Methyl Tenofovir Fumarate (Mixture of Diastereomers) | Mono poc-isopropyl-Tenofovir fumarate salt | Tenofovir disoproxil phosphate | Tenofovir Mono-POC methyl ester | Tenofovir Alafenamide Dimer impurity | Tenofovir Impurity 36 (RSR) 2,3-dihydroxysuccinate salt | Tenofovir Impurity 65 | Tenofovir Disoproxil T8 Impurity | Tenofovir Impurity 89 | Mono-POC Isopropyl Tenofovir | Tenofovir Impurity 59 | Tenofovir alafenamide lactose Millard Reaction product-3 | Desmethyl Tenofovir disoproxil | Tenofovir disoproxil impurity L | Tenofovir alafenamide Methyl ester impurity | Tenofovir Disoproxil (S)-Isomer fumarate salt | TAF methyl ester | Tenofovir Alfenamide Amadori Rearrangement product | Tenofovir disoproxil impurity L fumarate | Tri-POC Tenofovir Dimer | Tenofovir Isopropyl Carbamate | Tenofovir alafenamide impurity | Tenofovir Bis ((R)-9-(2-Hydroxypropyl)adenine) dimer Acetate salt | Tenofovir Disoproxil T7 Impurity | Tenofovir Alafenamide Dimer Impurity II | Diethylaminocarboxymethyl POC Tenofovir Fumarate | TenofovirDisoproxil Ethyl fumarate Impurity | Tenofovir Mono POC Dimer Diethyl amine salt | Tenofovir alafenamide Impurity 2 | Tenofovir Impurity 98 | Tenofovir Impurity 39 (RRR) 2,3-dihydroxysuccinate salt | Tenofovir alafenamide Impurity 5 | nPOC-POC Tenofovir Fumarate | Tenofovir Disoproxil Isopropoxycarbonyl | Tenofovir EP Impurity C Succinate | Tenofovir Impurity 59-D6 | MOC-POC Tenofovir Fumarate | Tenofovir Disoproxil Fumarate USP RC J | Mono-POC Ethyl Tenofovir | Tenofovir Disoproxil T11 Impurity | Tenofovir alafenamide Impurity 1 | Tenofovir alafenamide monofumarate | Tenofovir Disoproxil T12 Impurity | Tenofovir alafenamide lactose Millard Reaction product-2 | Tenofovir Alanine ester impurity | Tenofovir Alafenamide fumarate | Tenofovir isomer 6&1 | Tenofovir alafenamide Impurity 3 | Ethyl Tenofovir Impurity | Tenofovir Alafenamide N-hydroxy methyl impurity |