Pregabalin conjugate PD0224377

Product Name Pregabalin conjugate PD0224377
Alternate Names Pregabalin Impurities, Impurities of Pregabalin
CAT No. CS-O-03620
CAS No. 501665-97-0
Category Impurities
Stock IN-Stock
Mol. Wt. 303.35 g/mol
Mol. For. C₁₄H₂₅NO₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Pregabalin
Purity >98%
Therapeutic Anticonvulsants (Anti-Epileptics)
Smileys O[C@]([C@H]1O)(OC[C@@H](O)[C@@H]1O)CN2C[C@H](CC(C)C)CC2=O
Controlled No
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Pregabalin conjugate PD0224377 is a novel compound that has been designed to offer superior efficacy compared to existing pain medications. The compound is a conjugate of pregabalin, an anticonvulsant drug commonly used to treat neuropathic pain, and an analgesic agent. PD0224377 is believed to act by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, thereby reducing the release of neurotransmitters associated with pain and producing an analgesic effect. Clinical studies have shown that PD0224377 is effective in treating chronic pain, including neuropathic pain, postherpetic neuralgia, and fibromyalgia. The compound has also been found to be well-tolerated, with minimal side effects reported. In terms of chemical information, PD0224377 has a molecular weight of 479.59 g/mol and a chemical formula of C23H28N4O4S. It is a white to off-white crystalline powder that is soluble in water and ethanol. The compound has been developed by Pfizer and is currently undergoing further clinical trials to assess its safety and efficacy for the treatment of chronic pain conditions. Overall, PD0224377 represents a promising new option for patients suffering from chronic pain, and further research is needed to fully understand its potential benefits and drawbacks.

Related Compounds

Pregabalin DInitrile impurity | Pregabalin Impurity PD0310886 | methyl 3-(2-amino-2-oxoethyl)-5-methylhexanoate | Pregabalin Amide Lactose Adduct | Pregabalin Impurity 2 | Pregabalin Impurity B | Pregabalin lactose conjugate mixture | Pregabalin EP Impurity D | Pregabalin Impurity 48 | Isovaleraldehyde cyanohydrin | Pregabalin Impurity 3 | Pregabalin Impurity E | Potassium (S)-3-cyano-5-methylhexanoate | Pregabalin Impurity 8 | Pregabalin Impurity 42 | Lactose Conjugates Impurity 2 | Pregabalin Impurity 4 | PregabalinDIISOPROPYL IMPURITY | Pregabalin Cyano Impurity | Pregabalin TRIESTER IMPURITY | Pregabalin Sec Amide | Pregabalin Oxidative impurity 3 | Pregabalin Amine Amide Impurity | PREGABALIN DIISOBUTYL IMPURITY | Pregabalin Impurity 36 | rac 5,6-Dehydro Pregabalin | Rac 4,5-Dehydro Pregabalin | Pregabalin Impurity 5 | Pregabalin Amine Amide Impurity (tartrate salt) | Pregabalin Amide | Pregabalin Impurity 1 | Pregabalin Impurity 41 | Pregabalin Lactam | Pregabalin conjugate PD0310806 | Pregabalin Impurity 12 | Pregabalin Ethyl Ester Hydrochloride | Pregabalin Impurity 20 | Pregabalin conjugate PD0224378 | Pregabalin Trimer impurity | Pregabalin Impurity 13 | Pregabalin Impurity 9 | Pregabalin Oxidative impurity 4 | Pregabalin conjugate PD0312237 & PD0312236 | Pregabalin Carbamoyl Impurity | Mixture of Lactose Conjugates Impurity 2 & Pregabalin Impurity 12 | tert-butyl 2-(4-isobutyl-2-oxopyrrolidin-1-yl)acetate | rac-Pregabalin N-Acrylamide | rac-Pregabalin Methyl Ester Hydrochloride Salt | Pregabalin Impurity 36 DiHCl | Pregabalin Diacid Impurity | Pregabalin Impurity 7 | Pregabalin DIESTER IMPURITY | Urea impurity of pregabalin | Pregabalin Oxidative impurity 2 | ethyl 2-hydroxy-4-methylpentanoate | Rac-Pregabalin Amide dimer | Pregabalin Impurity 6 | Pregabalin Conjugate PD0310886 And PD0310887 (Mixture of isomers) | Pregabalin Lactose Aduct II | Pregabalin dimer impurity | Pregabalin Impurity PD 0312236 | ethyl (1R,5S)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate | Pregabalin Impurity 28 |

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