Propylthiouracil D5
| Product Name | Propylthiouracil D5 |
|---|---|
| CAT No. | CS-O-15087 |
| CAS No. | 1189423-94-6 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 175.26 g/mol |
| Mol. For. | C₇H₅D₅N₂OS |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Purity | 95% |
| Smileys | O=C(N1)C=C(NC1=S)CC([2H])([2H])C([2H])([2H])[2H] |
| Canonical Smiles | CCCC1=CC(=O)NC(=S)N1 |
| InchIKey | KNAHARQHSZJURB-ZBJDZAJPSA-N |
| Inchl | InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)/i1D3,2D2 |
| IUPAC | 6-(2,2,3,3,3-pentadeuteriopropyl)-2-sulfanylidene-1H-pyrimidin-4-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Propylthiouracil D5 is a deuterated analog of Propylthiouracil, which is an anti-thyroid drug used to treat hyperthyroidism. It is a white to off-white crystalline powder with a molecular weight of 184.27 g/mol. Propylthiouracil D5 is used for research purposes and is not intended for human consumption.
The primary use of Propylthiouracil D5 is in pharmacokinetic studies, where it is used as an internal standard for the quantification of Propylthiouracil levels in biological samples. Deuterium is a stable isotope of hydrogen, and the incorporation of deuterium into Propylthiouracil D5 improves the accuracy and precision of the analytical method used for quantification.
Propylthiouracil D5 is a thiourea derivative and functions as an inhibitor of thyroid hormone synthesis. It works by inhibiting the enzyme thyroperoxidase, which is responsible for the incorporation of iodine into tyrosine residues in the thyroid gland. This leads to a decrease in the production of thyroid hormones, ultimately resulting in the treatment of hyperthyroidism.
In conclusion, Propylthiouracil D5 is a useful tool for researchers conducting pharmacokinetic studies on Propylthiouracil. Its chemical properties allow for precise quantification of Propylthiouracil levels in biological samples, and its mechanism of action as a thyroid hormone inhibitor makes it an essential drug in the treatment of hyperthyroidism.
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