Spironolactone impurity D

Chemical Name Spironolactone impurity D
Alternate Names Spironolactone Impurities, Impurities of Spironolactone
CAT No. CS-O-10706
CAS Registry# Not Available
Category Impurities
Stock IN-Stock
Mol. Wt. 448.64 g/mol
Mol. For. C₂₄H₃₂O₄S₂
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Spironolactone
Purity 98.4
Therapeutic Anti-Hypertensives
Smileys C[C@@]12[C@](OC3=O)(CC3)CC[C@@]1([H])[C@@]([C@@H](CC4=CC5=O)SSC(C)=O)([H])[C@]([C@]4(CC5)C)([H])CC2
Controlled No
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Spironolactone is a medication that is commonly used to treat hypertension, edema, and other conditions related to fluid retention. However, during the manufacturing process, impurities may be generated that can affect the purity and effectiveness of the drug. One such impurity is Spironolactone Impurity D. Spironolactone Impurity D, also known as 7α-thiomethylspironolactone, is a byproduct of the synthesis of Spironolactone. This impurity is usually present in small amounts in Spironolactone formulations, and its levels are closely monitored during the manufacturing process to ensure that they do not exceed regulatory limits. From a chemical perspective, Spironolactone Impurity D is a derivative of Spironolactone that contains a sulfur atom and a methyl group attached to the 7α position of the steroid nucleus. This impurity is structurally similar to Spironolactone, but it has a slightly different pharmacological profile. While Spironolactone Impurity D is not itself an active pharmaceutical ingredient, it can still affect the safety and efficacy of Spironolactone formulations. Therefore, it is important to carefully control the levels of this impurity during the manufacturing process and to monitor its presence in finished products.

Related Compounds

Spironolactone EP impurity A | Spironolactone EP impurity E | Spironolactone EP impurity I | Spironolactone impurity H | Spironolactone EP impurity G | Spironolactone EP impurity C | Spironolactone Epimer Mixture | Spironolactone Impurity 2 | Spironolactone acid | Spironolactone EP impurity B |

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