Tenidap 13C6

[13C6]-Tenidap is a stable isotope-labeled version of Tenidap, a non-steroidal anti-inflammatory drug (NSAID) that belongs to the family of cyclooxygenase (COX) inhibitors. It is used in various research studies, particularly in pharmacokinetic and metabolic studies to determine the pharmacological behavior of the drug in vivo. The isotopic labeling of [13C6]-Tenidap involves the replacement of six carbon atoms in the molecule with the stable isotope carbon-13, which allows for accurate quantification and identification of the drug and its metabolites in biological samples using mass spectrometry. This technique is commonly used in drug development to better understand the absorption, distribution, metabolism, and elimination (ADME) of drugs in the body. The chemical properties of [13C6]-Tenidap are similar to its unlabeled counterpart, with a molecular weight of 383.45 g/mol and a chemical formula of C19H16N2O3S. Its mechanism of action involves the inhibition of COX enzymes, which are responsible for the production of prostaglandins, leading to the reduction of inflammation and pain. In conclusion, [13C6]-Tenidap is a valuable research tool that helps to provide insights into the pharmacokinetics and metabolism of Tenidap and other NSAIDs. Its isotopic labeling allows for accurate quantification and identification of the drug and its metabolites in biological samples, making it an essential component of pharmacological research.