Tofacitinib Dihydro Impurity

Product Name Tofacitinib Dihydro Impurity
Alternate Names Tofacitinib Impurities, Impurities of Tofacitinib
CAT No. CS-T-89311
CAS No. 1640972-35-5
Category Impurities
Stock IN-Stock
Mol. Wt. 314.39 g/mol
Mol. For. C₁₆H₂₂N₆O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Tofacitinib
Therapeutic Anti-Cancer / Oncology
Smileys N#CCC(N1C[C@H](N(C2=C3C(NCC3)=NC=N2)C)[C@H](C)CC1)=O
Canonical Smiles CC1CCN(CC1N(C)C2=NC=NC3=C2CCN3)C(=O)CC#N
InchIKey PEURVXMHTIUQCG-UHFFFAOYSA-N
Inchl InChI=1S/C16H22N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h10-11,13H,3-5,7-9H2,1-2H3,(H,18,19,20)
IUPAC 3-[3-[6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl(methyl)amino]-4-methylpiperidin-1-yl]-3-oxopropanenitrile
Controlled No
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5,6-Dihydro Tofacitinib, also known as Tofacitinib citrate or Xeljanz, is a drug used in the treatment of rheumatoid arthritis and psoriatic arthritis. It belongs to the class of Janus kinase (JAK) inhibitors, which block the activity of enzymes responsible for inflammation and joint damage. Chemically, 5,6-Dihydro Tofacitinib is a white to off-white crystalline powder, soluble in water and ethanol. It has a molecular weight of 504.9 g/mol and a chemical formula of C16H20N6O•C6H8O7. The recommended dosage of 5,6-Dihydro Tofacitinib is 5 to 10 mg, taken orally twice daily with or without food. It is important to follow the dosage instructions provided by a healthcare professional to avoid any potential side effects. Studies have shown that 5,6-Dihydro Tofacitinib is an effective treatment option for patients with rheumatoid arthritis and psoriatic arthritis, with significant improvement in symptoms such as joint pain, swelling, and stiffness. However, it is important to note that this drug may also have potential side effects such as infections, increased risk of cancer, and liver damage. In conclusion, 5,6-Dihydro Tofacitinib is a potent drug used in the treatment of arthritis with a mechanism of action that targets enzymes responsible for inflammation. It is important to use this drug under the guidance of a healthcare professional and monitor potential side effects to ensure its safe and effective use.

Related Compounds

Tofacitinib impurity Z | Tofacitinib Hydroxy Impurity | Tofacitinib impurity G | Tofacitinib Impurity 57 | Tofacitinib N-oxide | Tofacitinib impurity V | Tofacitinib Impurity 6 | Tofacitinib Nitroso Impurity 1 | Tofacitinib impurity T | Tofacitinib impurity J | Tofacitinib Related Compound 29 | Tofacitinib- Keto Impurity | N,4-dimethyl-1-nitrosopiperidin-3-amine | Tofacitinib N-hydroxy impurity | Tofacitinib Related Compound 26 HCl | Tofacitinib Impurity 29 | Tofacitinib Diastereomer | Tofacitinib Impurity 16 | Tofacitinib butyl ester impurity | Tofacitinib Impurity 36 | N-(1-benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide | Tofacitinib impurity I | Tofacitinib formyl impurity | Tofacitinib Nitroso Impurity | Tofacitinib Diastereomer-1 and 2 | Tofacitinib impurity C | Tofacitinib S,S Isomer | TOFACITINIB IMPURITY TOF-IV | Tofacitinib Nitroso Impurity 4 | N-Nitroso Tofacitinib Amine Impurity | Tofacitinib related compound 6 | N-methyl-N-(4-methylpyridin-3-yl)nitrous amide | Tofacitinib Dihydro Citricacid salt impurity | Tofacitinib Nitroso Impurity 5 | N-methyl-N-(4-methylpiperidin-3-yl)nitrous amide | Tofacitinib Nitroso Impurity 2 | Tofacitinib Nitroso Impurity 3 | Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4R)) | Tofacitinib impurity P | Tofacitinib impurity N | Tofacitinib N- acid Impurity | N-methyl-N-(4-methyl-1-nitrosopiperidin-3-yl)nitrous amide | Tofacitinib impurity K | Tofacitinib N-Nitroso benzyl intermediate |

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