trans-Epoxyphytomenadione
| Product Name | trans-Epoxyphytomenadione |
|---|---|
| CAT No. | CS-K-00145 |
| CAS No. | 85955-78-8 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 466.7 . g/mol |
| Mol. For. | C31 H46 O3 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | CC(C)CCCC(C)CCCC(C)CCCC(=CCC12C(=O)C3=CC=CC=C3C(=O)C1(O2)C)C |
| Canonical Smiles | CC(C)CCCC(C)CCCC(C)CCCC(=CCC12C(=O)C3=CC=CC=C3C(=O)C1(O2)C)C |
| InchIKey | KUTXFBIHPWIDJQ-BTPXSFBUSA-N |
| Inchl | InChI=1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-,30-,31+/m1/s1 |
| IUPAC | (1aR,7aS)-7a-methyl-1a-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl]naphtho[2,3-b]oxirene-2,7-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Trans-Epoxyphytomenadione, also known as trans-EPMK, is a synthetic analog of vitamin K that is used primarily as a procoagulant agent in the treatment of bleeding disorders. It is a water-soluble compound that belongs to the class of naphthoquinone derivatives. The compound is structurally similar to phytomenadione, also known as vitamin K1, but has an additional epoxy group on the side chain.
The mechanism of action of trans-EPMK involves the activation of coagulation factors II, VII, IX, and X, which are involved in the formation of blood clots. The compound works by promoting the gamma-carboxylation of glutamic acid residues on these factors, which is essential for their biological activity. The activation of these factors ultimately leads to the formation of thrombin, which converts fibrinogen to fibrin, thereby promoting blood clotting.
Trans-EPMK is typically administered intravenously, and it may be used in the treatment of bleeding disorders such as warfarin overdose, liver disease, and hemorrhagic disease of the newborn. It is also used in the management of bleeding during surgery, trauma, and other medical procedures.
Overall, trans-EPMK is an important procoagulant agent that plays a critical role in the management of bleeding disorders. Its chemical properties and mechanism of action make it a valuable tool for physicians and healthcare providers in the treatment of patients with these conditions.
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