Triciribine 13CD3 phosphate

Triciribine 13CD3 phosphate is a phosphorylated analogue of Triciribine, an experimental drug that has been investigated for its potential anti-cancer properties. Like Triciribine, Triciribine 13CD3 phosphate is a potent inhibitor of Akt, a protein kinase that plays a critical role in regulating cell proliferation and survival. By blocking Akt signaling, Triciribine 13CD3 phosphate can induce cell death in cancer cells and inhibit tumor growth. Triciribine 13CD3 phosphate is a stable, isotopically labeled compound that contains three deuterium atoms in place of three hydrogen atoms. This labeling allows for precise tracking of the drug in biological systems, which can help researchers better understand its pharmacokinetics and mechanism of action. In terms of usage, Triciribine 13CD3 phosphate is primarily used in preclinical studies to investigate its potential as an anti-cancer agent. Researchers may use the drug to study its effects on cancer cell lines or in animal models of cancer. The isotopic labeling of the drug also makes it useful for pharmacokinetic studies, which can help inform dosing and administration strategies for future clinical trials. Overall, Triciribine 13CD3 phosphate is a promising experimental drug that has shown potential as an anti-cancer agent. Its isotopic labeling allows for precise tracking of the drug in biological systems, which can aid in preclinical studies and inform future clinical trials.