Emtricitabine Impurity
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For Research & Analytical Purposes. Not for Personal use.
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CAT No. CS-T-47837
CAS No. 764659-72-5
Research Use
Storage: Store at refrigerator (2-8°C) for long term storage
Hazard: Refer MSDS for accurate information.
Emtricitabine Impurity Product Information
Emtricitabine Impurity is listed under Impurity and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Emtricitabine. The product is supplied by Clearsynth under CAT No. CS-T-47837.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.
Technical Data
Product Name
Emtricitabine Impurity
CAS No.
764659-72-5
CAT No.
CS-T-47837
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C18H26FN3O4S
Molecular Weight
399.5
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C1N([C@H]2O[C@@H](C(O[C@H](C[C@H](C)CC3)[C@@H]3C(C)C)=O)SC2)C=C(F)C(N)=N1
IUPAC Name
(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ester
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Regulatory Description
Emtricitabine Impurity is chemically (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ester. Emtricitabine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Emtricitabine Impurity can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Emtricitabine.
Overview
"An intermediate in the synthesis of Emtricitabine (). A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine . "
Synonyms
Emtricitabine Menthyl Ester Impurity
Application Notes
"An intermediate in the synthesis of Emtricitabine (). A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine . "
References
"Schinazi, R,F,, et al,: Antimicrob, Ag, Chemother,, 36, 2423 (1992), Shockeor, J,P,, et al,: Xenobioica, 26, 189 (1996), Feng, J,Y,, et al,: FASEB J,, 13, 1511 (1999), Molina, J,-M,, et al,: J, Infec, Dis,, 182, 599 (2000)"
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