N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester
Added to RFQ
For Research & Analytical Purposes. Not for Personal use.
Packaging & Handling
Indicative product packaging is shown for visual reference. Actual packaging may vary based on pack size, quantity, storage condition and shipping requirements.
Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for complete information.
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester Product Information
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester is listed under Stable Isotopes and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-98958.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.
Technical Data
Product Name
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester
CAS No.
1874196-88-9
CAT No.
CS-T-98958
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C18H16D5N2O7P
Molecular Weight
413.37
Category
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for complete information.
Description
Regulatory Description
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester is supplied with detailed characterization data compliant with regulatory guideline. N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester can be used for analytical method development, method validation (AMV), Quality Control (QC), ANDA-related analytical work, and commercial pharmaceutical research applications.
Overview
"N-???[(S)???-???(4-???Nitrophenoxy)???phenoxy-???2,???3,???4,???5,???6-???d5-???phosphinyl]???-???L-???Alanine-d5 1-???Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5 (P839643), an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-b-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase."
Synonyms
N-[(S)-(4-Nitrophenoxy)phenoxy-2,3,4,5,6-d5-phosphinyl]-L-Alanine-d5 1-Methylethyl Ester
Application Notes
"N-???[(S)???-???(4-???Nitrophenoxy)???phenoxy-???2,???3,???4,???5,???6-???d5-???phosphinyl]???-???L-???Alanine-d5 1-???Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5 (P839643), an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-b-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase."
Product Applications & Regulatory Search Terms
Useful product, supplier and regulatory search terms for this reference standard.