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Sitagliptin impurity L

ISO 17034:
Catalog Number : CS-AQ-00105
CAS Number : 851307-12-5
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What is the Chemical Information of Sitagliptin impurity L?

Chemical Name : Sitagliptin impurity L
Category : Impurities
Therapeutic : Antibiotics

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Sitagliptin, sold under the brand name Januvia among others, is an anti-diabetic medication used to treat type 2 diabetes. In the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. It is taken by mouth. It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet XR).Common side effects include headaches, swelling of the legs, and upper respiratory tract infections. Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain. Whether use in pregnancy or breastfeeding is safe is unclear. It is in the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by increasing the production of insulin and decreasing the production of glucagon by the pancreas.Sitagliptin was developed by Merck & Co. and approved for medical use in the United States in 2006. In 2019, it was the 88th most commonly prescribed medication in the United States, with more than 8\u00a0million prescriptions.
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Canonical SMILES : CC(C)(C)OC(=O)NC(CC1=C(C=C(C=C1)F)F)CC(=O)O
Isomeric SMILES : CC(C)(C)OC(=O)N[C@H](CC1=C(C=C(C=C1)F)F)CC(=O)O
InChI : InChI=1S/C15H19F2NO4/c1-15(2,3)22-14(21)18-11(8-13(19)20)6-9-4-5-10(16)7-12(9)17/h4-5,7,11H,6,8H2,1-3H3,(H,18,21)(H,19,20)/t11-/m1/s1
InchIKey : LUYHWLQWAVCDNA-LLVKDONJSA-N
IUPAC Name : (3R)-4-(2,4-difluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Exact Mass : 315.12821441
EC Number : 851-950-5

What are the Impurities of Sitagliptin ?

CAT NO. COMPOUND CAS NO. CATEGORY
CS-T-73299 3-Desamino-3,4-dehydro Sitagliptin 1675201-14-5 Sitagliptin Impurities
CS-O-34792 Sitagliptin tartrate hemihydrate NA Sitagliptin Impurities
CS-O-41611 (S)-Sitagliptin acetate NA Sitagliptin Impurities
CS-O-03409 Sitagliptin Hydrochloride 486459-71-6 Sitagliptin API Standards
CS-P-00287 (S)-Sitagliptin Hydrochloride NA Sitagliptin Chiral
CS-P-00283 Sitagliptin-N-sulfate 940002-57-3 Sitagliptin Metabolites
CS-O-43080 Sitagliptin Morpholine Intermediate-III 2248445-08-9 Sitagliptin Intermediates
CS-ER-01961 Sitagliptin System Suitability Mixture(Secondary Standards traceble to USP) NA Sitagliptin Secondary Standards
CS-O-31560 Sitagliptin Base 486460-32-6 Sitagliptin API Standards
CS-TB-14828 4-Desfluoro Sitagliptin 1345822-87-8 Sitagliptin Impurities
CS-O-36495 Sitagliptin+ Metformin Imp 4 NA Sitagliptin Impurities
CS-O-02387 Sitagliptin phosphate (Monohydrate) 654671-77-9 Sitagliptin Impurities
CS-EO-01276 Sitagliptin Impurity 28 1283583-85-6 Sitagliptin Impurities
CS-O-02325 Sitagliptin Phosphate 654671-78-0 Sitagliptin API Standards
CS-EO-01488 Sitagliptin Enamine Impurity 767340-03-4 Sitagliptin Impurities
CS-AQ-00107 Sitagliptin impurity R 486459-98-7 Sitagliptin Impurities
CS-O-08193 Sitagliptin EP Impurity B 486460-31-5 Sitagliptin Impurities
CS-O-08191 Sitagliptin EP Impurity E 936630-57-8 Sitagliptin Impurities
CS-T-93839 Sitagliptin EP Impurity C Phosphate 1345822-86-7 Sitagliptin Impurities
CS-AQ-00102 Sitagliptin impurity I NA Sitagliptin Impurities
CS-T-60052 Sitagliptin Impurity H 764667-65-4 Sitagliptin Impurities
CS-O-34315 rac-Sitagliptin-d4 823817-56-7 (Unlabeled) Sitagliptin Stable Isotopes
CS-AQ-00104 Sitagliptin impurity K NA Sitagliptin Impurities
CS-EO-01819 Sitagliptin Impurity 61 1620129-74-9 Sitagliptin Impurities
CS-O-41913 Sitagliptin Pyrazine Impurity NA Sitagliptin Impurities
CS-AQ-00099 Sitagliptin impurity D NA Sitagliptin Impurities
CS-O-06975 Sitagliptin D4 phosphate 1432063-88-1 Sitagliptin Stable Isotopes
CS-P-00285 Sitagliptin impurity N NA Sitagliptin Impurities
CS-P-00280 (R)-Sitagliptin Methyl-Ester Impurity 881995-69-3 Sitagliptin Impurities
CS-T-64537 N-Acetyl Sitagliptin-d3 1795785-80-6 Sitagliptin Stable Isotopes
CS-EO-00434 Sitagliptin EP Impurity A 823817-55-6 Sitagliptin Impurities
CS-AQ-00101 Sitagliptin impurity G 54608-52-5 Sitagliptin Impurities
CS-O-43079 Sitagliptin Morpholine Intermediate-II 2248445-00-1 Sitagliptin Intermediates
CS-EO-00173 (R)-Sitagliptin N-Boc-Methyl-Ester Impurity 881995-73-9 Sitagliptin Impurities
CS-T-49555 N-Boc-Sitagliptin 486460-23-5 Sitagliptin Intermediates
CS-P-00321 Sitagliptin Acid impurity 1204818-19-8 Sitagliptin Impurities
CS-EG-00792 Sitagliptin containing impurity A(Y0001811) NA Sitagliptin EP Standards
CS-O-39565 Sitagliptin D6 1133211-99-0 Sitagliptin Stable Isotopes
CS-O-16935 Sitagliptin Triazecine Analog 2088771-61-1 Sitagliptin Impurities
CS-O-41242 Nitroso Sitagliptin NA Sitagliptin Impurities
CS-T-95811 Oxo Sitagliptin NA Sitagliptin Impurities
CS-AQ-00103 Sitagliptin impurity J NA Sitagliptin Impurities
CS-O-08196 Sitagliptin N-Acetyl Impurity 1379666-94-0 Sitagliptin Impurities
CS-O-02775 Sitagliptin D4 hydrochloride 1426173-93-4 (freebase) Sitagliptin Stable Isotopes
CS-AQ-00108 Sitagliptin FP Impurity D 1253056-18-6 Sitagliptin Impurities
CS-O-40431 SITAGLIPTIN FORMIC ACID ADDUCT NA Sitagliptin Impurities
CS-ZG-88020 Sitagliptin EP Impurity C 1345822-86-7 Sitagliptin Impurities
CS-P-09023 Sitagliptin Impurity 62 2379621-81-3 Sitagliptin Impurities
CS-EB-01969 Sitagliptin System Suitability Mixture (R090K0) NA Sitagliptin USP Standards
CS-P-08948 Sitagliptin Impurity 39 1485732-85-1 Sitagliptin Impurities