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Ethyl 2-(triphenylphosphoranylidene)propanoate

ISO 17034:
Catalog Number : CS-M-56777
CAS Number : 5717-37-3
Status : Available
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Chemical Information

Chemical Name : Ethyl 2-(triphenylphosphoranylidene)propanoate
Category : Impurity Standards
Purity : >98%
Synonyms : Sofosbuvir Impurity
Molecular Weight : 362.41 mol/g
Molecular Formula : C23H23O2P
Application : Impurity in commercial preparations of Sofosbuvir.
Therapeutic : Antiretroviral / Anti-HIV

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Hazardous Compound : No

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Additional Information

Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth.

Common side effects include fatigue, headache, nausea, and trouble sleeping. Side effects are generally more common in interferon-containing regimens.:\u200a7\u200a Sofosbuvir may reactivate hepatitis B in those who have been previously infected. In combination with ledipasvir, daclatasvir or simeprevir, it is not recommended with amiodarone due to the risk of an abnormally slow heartbeat. Sofosbuvir is in the nucleotide analog family of medications and works by blocking the hepatitis C NS5B protein.

Sofosbuvir was discovered in 2007 and approved for medical use in the United States in 2013. It is on the World Health Organization's List of Essential Medicines.

Canonical SMILES : CCOC(=O)C(=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C
Isomeric SMILES : CCOC(=O)C(=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C
InChI : InChI=1S/C23H23O2P/c1-3-25-23(24)19(2)26(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18H,3H2,1-2H3
IUPAC Name : ethyl 2-(triphenyl-lambda5-phosphanylidene)propanoate
Exact Mass : 362.14356697
Hazard Class : Acute Tox. 4 (25%)
EC Number : 227-215-4

Related compounds of Ethyl 2-(triphenylphosphoranylidene)propanoate

CS-O-15621 Chloro Sofosbuvir Desphosphate 1496551-72-4 Impurity Standards
CS-O-11152 Ethyl sofosbuvir 1064684-30-5 Impurity Standards
CS-T-84999 Sofosbuvir 3’,5’-Bis-(S)-phosphate 1337482-17-3 Impurity Standards
CS-O-32142 Sofosbuvir Benzoyl Cytidine 817204-32-3 Impurity Standards
CS-O-11153 Sofosbuvir Chloro Analogue 1496552-51-2 Impurity Standards
CS-O-11150 Sofosbuvir D-Alaninate 1064684-71-4 Impurity Standards
CS-O-14747 Sofosbuvir Degradation Impurity 1 1015073-43-4 Impurity Standards
CS-O-11148 Sofosbuvir Dimer 1256490-29-5 Impurity Standards
CS-O-16052 Sofosbuvir Impurity 1351925-15-9 Impurity Standards
CS-DG-00023 Sofosbuvir impurity 12 114262-49-6 Impurity Standards
CS-DG-00022 Sofosbuvir impurity 19 1337482-15-1 Impurity Standards
CS-DG-00027 Sofosbuvir impurity 3 863329-62-8 Impurity Standards
CS-DG-00021 Sofosbuvir impurity 32 1157884-58-6 Impurity Standards
CS-DG-00020 Sofosbuvir impurity 43 1520010-86-9(Freeacid) Impurity Standards
CS-DG-00026 Sofosbuvir impurity 5 863329-63-9 Impurity Standards
CS-DG-00025 Sofosbuvir impurity 6 874638-94-5 Impurity Standards
CS-DG-00024 Sofosbuvir impurity 9 944476-44-2 Impurity Standards
CS-O-33875 Sofosbuvir Impurity D NA Impurity Standards
CS-O-14752 Sofosbuvir L-alanitate (Mixture of Diasteriomers) 1190308-01-0 Impurity Standards
CS-O-11149 (R)-Sofosbuvir Pentafluorophenoxy Analogue 1334513-02-8 Impurity Standards
CS-O-14745 (S)-Sofosbuvir Pentafluorophenoxy Analogue 1256490-52-4 Impurity Standards
CS-O-15606 2-Alkene Sofosbuvir NA Impurity Standards
CS-T-92617 2(R)-Methyl Sofosbuvir 1496552-28-3 Impurity Standards