Camostat Mesylate

ISO 17034:
Catalog Number : CS-O-00543
CAS Number : 59721-29-8
Status : Available for immediate dispatch
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Product Information

Product Name : Camostat Mesylate
Category : API Standards
Purity : Not less than 95%
Molecular Weight : 494.52 mol/g
Molecular Formula : C₂₁H₂₆N₄O₈S
Application : "Orally active, non-peptide proteolitic enzyme inhibitor with anti-trypsin and anti-plasmin activities, related structurally to gabexate. Protease inhibitor."

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Hazardous Compound : No

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References : "Tamura; Y,; et al,: Biochem, Biophys, Acta; 484; 417 (1977); Takasugi; S,; et al,: Digestion; 24; 36 (1982);"
Canonical SMILES : CN(C)C(=O)COC(=O)CC1=CC=C(C=C1)OC(=O)C2=CC=C(C=C2)N=C(N)N.CS(=O)(=O)O
Isomeric SMILES : CN(C)C(=O)COC(=O)CC1=CC=C(C=C1)OC(=O)C2=CC=C(C=C2)N=C(N)N.CS(=O)(=O)O
InChI : InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
Related CAS : 59721-28-7 (Parent)
IUPAC Name : [4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate;methanesulfonic acid
Exact Mass : 494.14713497
Hazard Class : Skin Irrit. 2 (100%)
Description : Camostat mesylate is a methanesulfonate (mesylate) salt prepared from equimolar amounts of camostat and methanesulfonic acid. It is a serine protease inhibitor approved and marketed in Japan in 1985 for the alleviation of acute symptoms associated with chronic pancreatitis. In 1994, it was approved for the treatment of postoperative reflux esophagitis. It has a role as an anticoronaviral agent, an anti-inflammatory agent, an antifibrinolytic drug, an antihypertensive agent, an antineoplastic agent, an antiviral agent and a serine protease inhibitor. It contains a camostat(1+).
EC Number : 694-565-6