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Bumetanide



Chemical Properties of 'Bumetanide'

CAT No. :

CS-O-00982
CAS Registry No. : 28395-03-1
Category : API Standards
Molecular Weight: 364.42
Molecular Formula : C₁₇H₂₀N₂O₅S



OTHER INFORMATION of 'Bumetanide'
Purity : Not less than 98 %
Therapeutic : Anti-Hypertensives
Purity : Not less than 98 %
Therapeutic : Anti-Hypertensives
IUPAC Name :3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Applicationnotes :Bumetanide is a sulfamyl diuretic. The physiologic effect of bumetanide is by means of Increased Diuresis at Loop of Henle
Synonym :Not available
Smileys :CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Appearance :White to off white solid
Melting Point :230-231
Solubility :>54.7 [ug/mL]
Use Classification :Human Drugs -> EU pediatric investigation plans
Hazard Class :Skin Irrit. 2 (75%)
EC Number :249-004-6
UNII :0Y2S3XUQ5H
NCI Thesaurus Code :C28875
RXCUI :1808
MeSH Entry Terms :Bumedyl
Other Synonyms :bumetanide
Removed Synonyms :Bumethanide
Label Ingredient : BUMETANIDE
NDC Code :0185-0128-01, 0185-0128-05, 0185-0129-01, 0185-0129-05, 0185-0130-01, 0185-0130-05, 0409-1412-04, 0409-1412-10, 0409-1412-34, 0409-1412-40 ... total 167.
Metabolite Pathways :Bumetanide Action Pathway
Toxicity Summary :Overdosage can lead to acute profound water loss, volume and electrolyte depletion, dehydration, reduction of blood volume and circulatory collapse with a possibility of vascular thrombosis and embolism. Electrolyte depletion may be manifested by weakness, dizziness, mental confusion, anorexia, lethargy, vomiting and cramps. Treatment consists of replacement of fluid and electrolyte losses by careful monitoring of the urine and electrolyte output and serum electrolyte levels.
Drug Induced Liver Injury :bumetanide
Protein Binding :97%
Exact Mass :364.10929292
InChI :InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
InchIKey :MAEIEVLCKWDQJH-UHFFFAOYSA-N
Canonical SMILES :CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Isomeric SMILES :CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Product Description :Bumetanide is a member of the class of benzoic acids that is 4-phenoxybenzoic acid in which the hydrogens ortho to the phenoxy group are substituted by butylamino and sulfamoyl groups. Bumetanide is a diuretic, and is used for treatment of oedema associated with congestive heart failure, hepatic and renal disease. It has a role as a diuretic and an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. It is a sulfonamide, an amino acid and a member of benzoic acids.
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back


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This page contains information about Bumetanide , Bumetanide cas, Bumetanide synthesis, Bumetanide suppliers

What is Bumetanide ?
Bumetanide falls under API Standards of Bumetanide.Bumetanide is a sulfamyl diuretic. The physiologic effect of bumetanide is by means of Increased Diuresis at Loop of Henle
What is the CAS Number of Bumetanide?
The CAS Number of Bumetanide is 28395-03-1
Who are the suppliers of Bumetanide?
CLEARSYNTH is a worldwide supplier of Bumetanide

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