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Cinacalcet Hydrochloride



Chemical Properties of 'Cinacalcet Hydrochloride'

CAT No. :

CS-O-01101
CAS Registry No. : 364782-34-3
Category : API Standards
Molecular Weight: 393.87
Molecular Formula : C₂₂H₂₃ClF₃N



OTHER INFORMATION of 'Cinacalcet Hydrochloride'
Purity : Not less than 98%
Purity : Not less than 98%
IUPAC Name :N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Applicationnotes :An allosteric activator of CaSR
Synonym :Not available
References :"Shalhoub, V,, et al, 2003, Crit, Rev, Eukaryot, Gene Expr, 13: 89-106, ,Nemeth, E,F,, et al, 2004, J, Pharmacol, Exp, Ther, 308: 627-635, ,Liou, A,P,, et al, 2011, Am J Physiol Gastrointest Liver Physiol, [Epub ahead of print],"
Smileys :CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
Appearance :White to off white solid
Related CAS : 226256-56-0 (Parent)
Use Classification :Human drugs -> Cinacalcet Accordpharma -> EMA Drug Category
Hazard Class :Acute Tox. 4 (57.14%)
EC Number :620-490-5
UNII :1K860WSG25
NCI Thesaurus Code :C47450
RXCUI :384379
MeSH Entry Terms :alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride
Other Synonyms :Cinacalcet hydrochloride
Removed Synonyms :Cinacalcet
Label Ingredient : CINACALCET HYDROCHLORIDE
NDC Code :0904-7067-04, 16714-078-01, 16714-079-01, 16714-080-01, 16729-440-01, 16729-440-10, 16729-440-15, 16729-441-01, 16729-441-10, 16729-441-15 ... total 132.
Exact Mass :393.1471119
InChI :InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
InchIKey :QANQWUQOEJZMLL-PKLMIRHRSA-N
Canonical SMILES :CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
Isomeric SMILES :C[C@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
Product Description :Cinacalcet hydrochloride is a hydrochloride derived from equimolar amounts of cinacalcet and hydrogen chloride. It has a role as a calcimimetic and a P450 inhibitor. It derives from a cinacalcet.
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 15-Aug-2022
Taxes : Not Applicable
Refund Policy : 30-days money back
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 15-Aug-2022
Taxes : Not Applicable
Refund Policy : 30-days money back


More information about Cinacalcet


Cinacalcet, sold under the brand name Sensipar among others, is a medication used to treat tertiary hyperparathyroidism, parathyroid carcinoma, and primary hyperparathyroidism.

The most common side effects include nausea (feeling sick) and vomiting.

Cinacalcet acts as a calcimimetic (i.e., it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues.

Cinacalcet was approved in the United States in March 2004, and in the European Union in October 2004. It was the first allosteric G protein-coupled receptor modulator to enter the pharmaceutical market. In 2013, cinacalcet was the 76th top prescribed medicine in the United States.




This page contains information about Cinacalcet Hydrochloride , Cinacalcet Hydrochloride cas, Cinacalcet Hydrochloride synthesis, Cinacalcet Hydrochloride suppliers

What is Cinacalcet Hydrochloride ?
Cinacalcet Hydrochloride falls under API Standards of Cinacalcet.An allosteric activator of CaSR
What is the CAS Number of Cinacalcet Hydrochloride?
The CAS Number of Cinacalcet Hydrochloride is 364782-34-3
Who are the suppliers of Cinacalcet Hydrochloride?
CLEARSYNTH is a worldwide supplier of Cinacalcet Hydrochloride

List of Cinacalcet API Standards

Related compounds of Cinacalcet Hydrochloride

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