Mirtazapine Hemihydrate USP

ISO 17034:

Custom Quote

Instant Help

Catalog Number : CS-O-01869
CAS Number : 61337-67-5
Status : Available for immediate dispatch
Category : API Standards
Purity : >98%
Molecular Weight : 283.37 mol/g
Molecular Formula : C17H21N3O
Controlled Substance

ssThis product is under final analysis

This compound is currently under final analysis and hence the price is not available online.
You will receive an email from our team within 12 hours with the pricing and delivery information.

Shipping & Availability

Status : Available for immediate dispatch
COA :
[Login Needed]
MSDS :
[Login Needed]
Controlled Substance : Yes

More Information

Synonyms : 5-methyl-2;5;19-triazate1(15);8;10;12;16;18-hexaene hydrate;Mirtazapine Hemihydrate.
Payment mode : Credit / Debit / Purchase Order
Taxes : All prices are inclusive taxes
Refund Policy : 30 days money back guarantee
Canonical SMILES : CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Isomeric SMILES : CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
InChI : InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InchIKey : RONZAEMNMFQXRA-UHFFFAOYSA-N
IUPAC Name : 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene
Exact Mass : 265.157897619
Melting Point : 114-116 °C
Solubility : slightly soluble in water
Use Classification : Veterinary drugs -> Mirataz -> EMA Drug Category
Hazard Class : Acute Tox. 4 (100%)
Description : Mirtazapine is a benzazepine and a tetracyclic antidepressant. It has a role as an alpha-adrenergic antagonist, a serotonergic antagonist, a histamine antagonist, an anxiolytic drug, a H1-receptor antagonist and a oneirogen.
EC Number : 288-060-6
Toxicity Summary : **LD50** Oral LD50 was 830 mg/kg in male Swiss mice 24 hours after being administered mirtazapine. **Overdose information** Activated charcoal should be administered during an overdose to absorb excess mirtazapine. General supportive therapy should be employed, including maintenance of an adequate airway, oxygen therapy, and ventilation therapy. Vital signs and cardiac rhythm must be monitored. It is not advisable to induce vomiting. Gastric lavage with a large-bore orogastric tube with proper protection of the airway is recommended. There is no antidote for mirtazapine available currently. Consider the possibility of mirtazapine combined with other drugs in an overdose and ensure to contact the local poison control center for guidance on management. **Carcinogenesis** At higher than normal doses, mirtazapine increased the incidence of hepatocellular adenomas and carcinomas in male mice. The highest doses administered to the mice were about 20 and 12 times the maximum recommended human dose (MRHD). Hepatocellular tumors and thyroid follicular adenoma/cystadenomas in male rats occurred at an increased rate at a higher mirtazapine dose (60 mg/kg/day). In female rats, both the medium (20 mg/kg/day) and higher (60 mg/kg/day) doses of mirtazapine increased the rate of hepatocellular adenomas. The relevance of these findings in humans is not known at this time. **Impairment of Fertility** Mirtazapine was administered to rats at doses reaching 100 mg/kg (equivalent to 20 times the maximum recommended human dose) in a fertility study. There was no impact on mating and conception, however, there was a disturbance of reproductive (estrous) cycling at higher doses. These doses were measured to be at least 3 times the maximum recommended human dose. Loss of fetus before implantation in the uterus occurred when doses equivalent to 20 times the maximum recommended dose were administered. **Use in pregnancy** This drug is categorized as a pregnancy category C drug. No adequate studies in pregnant women have been conducted. In rats, an increased rate of post-implantation demise occurred with mirtazapine administration. Additionally, an increase in deaths of rat pups during the first 3 days of lactation with a decrease in pup birth weight was noted. Studies on animals are not always relevant to human response. Mirtazapine should be used during pregnancy only if the clinical need outweighs the possible risks to the fetus. **Use in nursing** Whether this drug is excreted in human milk is unknown. Many drugs are found excreted in human breast milk, therefore caution is advised if this drug is used during nursing.

We also have the following compounds available for commercial bulk quantities

CAT NO. COMPOUND CAS NO. CATEGORY
CS-O-02954 Acetophenone D5 28077-64-7 Stable Isotope Reagent
CS-T-47110 Acetylaniline D5 15826-91-2 Stable Isotopes
CS-T-48261 Aniline D5 4165-61-1 Stable Isotope Reagent
CS-O-41560 Benzene D6 D-Atom 99.5% 1076-43-3 NMR Solvent
CS-O-11242 Benzene-d6 1076-43-3 Stable Isotope Reagent
CS-T-48633 Benzeneacetonitrile D2 935-66-0 Stable Isotopes
CS-T-48678 Benzoic Acid D5 1079-02-3 Stable Isotope Reagent
CS-C-00287 Benzophenone-d10 22583-75-1 Stable Isotope Reagent
CS-BX-00300 Benzyl alcohol D5 68661-10-9 Stable Isotopes
CS-BX-00301 Benzyl alcohol D7 71258-23-6 Stable Isotopes
CS-O-10415 Benzyl bromide-d7 35656-93-0 Stable Isotope Reagent
CS-T-48831 Benzyl-d5 Bromide 71258-22-5 Stable Isotope Reagent
CS-O-10893 Bromobenzene D5 4165-57-5 Stable Isotope Reagent
CS-C-00153 Bromocyclopentane D9 35468-44-1 Stable Isotope Reagent
CS-T-50405 Catechol D4 103963-58-2 Stable Isotope Reagent
CS-T-50737 Chloroform-d 865-49-6 Stable Isotope Reagent
CS-CE-00821 Deuterium Bromide 13536-59-9 Stable Isotope Reagent
CS-T-52330 Deuterium Chloride 7698-05-7 Stable Isotope Reagent
CS-BX-00568 Dibromomethane D2 22117-86-8 Stable Isotope Reagent
CS-T-52810 Diethyl Methyl-d3-malonate 54840-57-2 Stable Isotopes
CS-O-03137 Dimethylamine D6 Hydrochloride 53170-19-7 Stable Isotope Reagent
CS-CX-00457 Diphenylmethanol D10 74563-01-2 Stable Isotopes
CS-T-54279 Ethanol-OD 925-93-9 Stable Isotope Reagent
CS-O-10421 Iodomethane-d3 865-50-9 Stable Isotope Reagent
CS-T-56839 Isopropanol D7 19214-96-1 Stable Isotope Reagent
CS-O-42348 methyl 2-(methoxy-d3)benzoate 2237235-31-1 Stable Isotope Reagent
CS-O-01232 Methyl-D3 Amine Hydrochloride 7436-22-8 Stable Isotope Reagent
CS-T-53653 N,N-Dimethyl-p-phenylenediamine-d6 1398066-19-7 Stable Isotope Reagent
CS-O-42939 N,N-Dimethylaniline-d11 85785-00-8 Stable Isotope Reagent
CS-T-49548 N-Boc-piperazine D8 1126621-86-0 Stable Isotope Reagent
CS-O-15212 Naphthalene D8 1146-65-2 Stable Isotopes
CS-T-52196 p-(Dimethyl-d6-amino)nitrosobenzene 1398065-85-4 Stable Isotopes
CS-O-16338 p-Toluic-2,3,5,6-D4 Acid 1219798-71-6 Stable Isotope Reagent
CS-T-60433 Phenethylamine D4 HCl 1631986-59-8 Stable Isotope Reagent
CS-T-60354 Phenol D5 4165-62-2 Stable Isotope Reagent
CS-BX-00365 Phenyl-D5-boronic acid 215527-70-1 Stable Isotopes
CS-BX-01153 Phenylacetic acid-α,α-d2 1076-07-9 Stable Isotopes
CS-O-02793 Piperazine-D8 Dihydrochloride 849482-21-9 Stable Isotope Reagent
CS-T-60800 Propionic Acid D3 55577-88-3 Stable Isotope Reagent
CS-R-00642 Propionic acid D5 60153-92-6 Stable Isotope Reagent
CS-T-85549 Propiophenone-d5 54419-23-7 Stable Isotopes
CS-O-15142 Sodium Deuteroxide 14014-06-3 Stable Isotope Reagent
CS-O-13174 Sulfuric Acid D2 13813-19-9 Stable Isotope Reagent
CS-C-00216 "Benzophenone-2,3,4,5,6-d5" 2694-78-2 Stable Isotopes
CS-CX-00453 "N,N-Dimethylaniline D6" 4019-61-8 Stable Isotopes
CS-T-53482 "1,1-Dimethyl-1-propanol D6" 75295-95-3 Stable Isotopes
CS-C-00175 "4-Bromoaniline-2,3,5,6-d4" 61357-76-4 Stable Isotopes
CS-T-59322 "4-Nitroaniline-2,3,5,6-D4" 64164-08-5 Stable Isotopes
CS-O-43154 (±)-1-Phenyl D5-Ethanol 90162-45-1 Stable Isotope Reagent
CS-O-43067 1-Bromo-4-iodo-2,3,5,6-tetradeuteriumbenzene 1147565-46-5 Stable Isotope Reagent
CS-O-42051 1-​(METHYL-​D3)​PIPERAZINE 2HCL 2043778-87-4 Stable Isotope Reagent
CS-T-94262 1,3-Dinitrobenzene-d4 54247-05-1 Stable Isotope Reagent
CS-T-49864 2-Bromopropane D6 52809-76-4 Stable Isotope Reagent
CS-T-49863 2-Bromopropane D7 39091-63-9 Stable Isotope Reagent
CS-C-00172 2-Methoxy-d3-benzaldehyde 56248-49-8 Stable Isotopes
CS-O-10078 2-Methylpropionic D7 Acid 223134-74-5 Stable Isotope Reagent
CS-O-42876 2-Phenylethan-1,1,2,2-d4-ol 107473-33-6 Stable Isotope Reagent
CS-O-42441 2-(METHOXY-D3)ANILINE 1398066-00-6 Stable Isotope Reagent
CS-T-67167 3-Bromoaniline D4 81395-17-7 Stable Isotopes
CS-T-67231 3-Bromonitrobenzene-d4 81395-16-6 Stable Isotopes
CS-O-39705 3-Chloro-2,4,5,6-tetradeuteroaniline 1027104-24-0 Stable Isotopes
CS-O-42469 3-(METHOXY-D3)ANILINE 1820607-08-3 Stable Isotope Reagent
CS-O-33121 4-amino-2,5,3,6-d4-phenol 70237-44-4 Stable Isotopes
CS-C-00162 4-Bromobenzoic-d4 Acid 787624-24-2 Stable Isotopes
CS-C-00199 4-Bromotoluene-2,3,5,6-d4 112484-85-2 Stable Isotope Reagent
CS-O-42491 4-(METHOXY-D3)ANILINE 1820684-56-7 Stable Isotope Reagent
CS-O-42492 4-(METHOXY-D3)BENZALDEHYDE 342611-04-5 Stable Isotope Reagent
CS-O-42292 4-[di(methyl-d3)amino]benzoic acid 1175002-09-1 Stable Isotope Reagent
CS-O-42300 5-bromo-1-(methyl-d3)-1H-indole 2140317-04-8 Stable Isotope Reagent