0.5 MG | x |
Save $ 19.00 |
$ 356.00
|
2.5 MG | x |
Save $ 84.00 |
$ 1,591.00
|
Chemical Properties of 'Tacrolimus 13CD2' |
|
CAT No. : |
CS-O-03122 |
CAS Registry No. : | 1356841-89-8 |
Category : | Isotope Labelled Compounds |
Molecular Weight: | 807.2 |
Molecular Formula : | C₄₃¹³CH₆₇D₂NO₁₂ |
OTHER INFORMATION of 'Tacrolimus 13CD2' |
|
Purity : | >98% |
Therapeutic : | Immunosuppressants |
IUPAC Name : | (1R,9S,12S,13R,14S,17R,18Z,21S,23S,24R,25S,27R)-17-(3,3-dideuterio(313C)prop-2-enyl)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone |
Applicationnotes : | "Labeled Tacrolimus, intended for use as an internal standard for the quantification of Tacrolimus by GC- or LC-mass spectrometry." |
Synonym : | Not Available |
Smileys : | CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC |
Appearance : | White to off white powder |
Other Synonyms : | 1356841-89-8 |
Exact Mass : | 806.49788496 |
InChI : | InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19-,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1/i1+1D2 |
InchIKey : | QJJXYPPXXYFBGM-OTZVSDQDSA-N |
Canonical SMILES : | CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC |
Isomeric SMILES : | [2H][13C](=CC[C@@H]1/C=C(\C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)/C)[2H] |
Custom Duty : | Applicable |
Port of Loading : | Canada |
Expected Dispatch : | 18-Aug-2022 |
Taxes : | Not Applicable |
Refund Policy : | 30-days money back |
Custom Duty : | Applicable |
Port of Loading : | Canada |
Expected Dispatch : | 18-Aug-2022 |
Taxes : | Not Applicable |
Refund Policy : | 30-days money back |
Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs.
Tacrolimus inhibits calcineurin, which is involved in the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, as part of the body's learned (or adaptive) immune response.
Looking for a discounted price or need more info for 'Tacrolimus 13CD2 (CS-O-03122)' ?
If you are looking for Bulk purchase, Discounted Price, etc. please share your email and the exact quantity you are looking for, our team will respond to you within 30 mins with all the required information.