ISO 17034:

Custom Quote

Instant Help

Catalog Number : CS-O-06170
CAS Number : 86-22-6
Status : Available for immediate dispatch
Category : API Standards
Purity : >98%
Molecular Weight : 319.24 mol/g
Molecular Formula : C16H19BrN2
Therapeutic : Antihistamine
List Price Online Price Size Stock Status Quantity

Shipping & Availability

Status : Available for immediate dispatch
[Login Needed]
[Login Needed]

More Information

Application : "Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria."
Synonyms : 3-(4-bromophenyl)-N;N-dimethyl-3-pyridin-2-yl-propan-1-amine
Payment mode : Credit / Debit / Purchase Order
Taxes : All prices are inclusive taxes
Refund Policy : 30 days money back guarantee
Canonical SMILES : CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2
Isomeric SMILES : CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2
InChI : InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
Related CAS : 980-71-2 (maleate (1:1))
IUPAC Name : 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Exact Mass : 318.07316
Color : Oily liquid with slightly yellow color
Odor : Characteristic amine-like
Melting Point : < 25 °C
Solubility : Freely soluble (maleate salt)
Use Classification : Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Hazard Class : Acute Tox. 4 (100%)
Description : Brompheniramine is pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis. It has a role as a H1-receptor antagonist and an anti-allergic agent. It is a member of pyridines and an organobromine compound.
Disposal Methods : SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
EC Number : 201-657-8
Vapor Pressure : 4.63X10-5 mm Hg at 25 °C (est)
Toxicity Summary : Oral, rat: LD50 = 318 mg/kg. Signs of overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.
Antidoteand Emergency Treatment : Emergency and supportive measures: Maintain an open airway and assist ventilation if necessary. Treat coma, seizures, hyperthermia, and atypical ventricular tachycardia if they occur. Monitor the patient for at least 6 to 8 hours after ingestion. Specific drugs and antidotes: There is no specific antidote for antihistamine overdose. As for anticholinergic poisoning, physostigmine has been used for treatment of severe delirium or tachycardia. However because antihistamine overdose carry a greater risk for seizures physostigmine is not recommended routinely. Sodium bicarbonate may be useful for myocardial depression ... . Decontamination: Administer activated charcoal orally if conditions are appropriate. Gastric lavage is not necessary after small to moderate ingestions if activated charcoal can be given promptly. Because of slowed gastrointestinal motility, gut decontamination procedures may be helpful even in late-presenting patients. Enhanced elimination: Hemodialysis, hemoperfusion, peritoneal dialysis, and repeat dose activated charcoal are not effective in removing antihistamines. /Antihistamines/
Human Toxicity Excerpts : /SIGNS AND SYMPTOMS/ In acute poisoning with H1 antagonists, their central excitatory effects constitute the greatest danger. The syndrome includes hallucinations, excitement, ataxia, incoordination, athetosis, and convulsions. Fixed, dilated pupils with a flushed face, together with sinus tachycardia, urinary retention, dry mouth, and fever, lend the syndrome a remarkable similarity to that of atropine poisoning. Terminally, there is deepening coma with cardiorespiratory collapse and death, usuallY within 2 to 18 hours. Treatment is along general symptomatic and supportive lines. /Histamine Antagonists: H1 Antagonists/

We also have the following compounds available for commercial bulk quantities

CS-O-02954 Acetophenone D5 28077-64-7 Stable Isotope Reagent
CS-T-47110 Acetylaniline D5 15826-91-2 Stable Isotopes
CS-T-48261 Aniline D5 4165-61-1 Stable Isotope Reagent
CS-O-41560 Benzene D6 D-Atom 99.5% 1076-43-3 NMR Solvent
CS-O-11242 Benzene-d6 1076-43-3 Stable Isotope Reagent
CS-T-48633 Benzeneacetonitrile D2 935-66-0 Stable Isotopes
CS-T-48678 Benzoic Acid D5 1079-02-3 Stable Isotope Reagent
CS-C-00287 Benzophenone-d10 22583-75-1 Stable Isotope Reagent
CS-BX-00300 Benzyl alcohol D5 68661-10-9 Stable Isotopes
CS-BX-00301 Benzyl alcohol D7 71258-23-6 Stable Isotopes
CS-O-10415 Benzyl bromide-d7 35656-93-0 Stable Isotope Reagent
CS-T-48831 Benzyl-d5 Bromide 71258-22-5 Stable Isotope Reagent
CS-O-10893 Bromobenzene D5 4165-57-5 Stable Isotope Reagent
CS-C-00153 Bromocyclopentane D9 35468-44-1 Stable Isotope Reagent
CS-T-50405 Catechol D4 103963-58-2 Stable Isotope Reagent
CS-T-50737 Chloroform-d 865-49-6 Stable Isotope Reagent
CS-CE-00821 Deuterium Bromide 13536-59-9 Stable Isotope Reagent
CS-T-52330 Deuterium Chloride 7698-05-7 Stable Isotope Reagent
CS-BX-00568 Dibromomethane D2 22117-86-8 Stable Isotope Reagent
CS-T-52810 Diethyl Methyl-d3-malonate 54840-57-2 Stable Isotopes
CS-O-03137 Dimethylamine D6 Hydrochloride 53170-19-7 Stable Isotope Reagent
CS-CX-00457 Diphenylmethanol D10 74563-01-2 Stable Isotopes
CS-T-54279 Ethanol-OD 925-93-9 Stable Isotope Reagent
CS-O-10421 Iodomethane-d3 865-50-9 Stable Isotope Reagent
CS-T-56839 Isopropanol D7 19214-96-1 Stable Isotope Reagent
CS-O-42348 methyl 2-(methoxy-d3)benzoate 2237235-31-1 Stable Isotope Reagent
CS-O-01232 Methyl-D3 Amine Hydrochloride 7436-22-8 Stable Isotope Reagent
CS-T-53653 N,N-Dimethyl-p-phenylenediamine-d6 1398066-19-7 Stable Isotope Reagent
CS-O-42939 N,N-Dimethylaniline-d11 85785-00-8 Stable Isotope Reagent
CS-T-49548 N-Boc-piperazine D8 1126621-86-0 Stable Isotope Reagent
CS-O-15212 Naphthalene D8 1146-65-2 Stable Isotopes
CS-T-52196 p-(Dimethyl-d6-amino)nitrosobenzene 1398065-85-4 Stable Isotopes
CS-O-16338 p-Toluic-2,3,5,6-D4 Acid 1219798-71-6 Stable Isotope Reagent
CS-T-60433 Phenethylamine D4 HCl 1631986-59-8 Stable Isotope Reagent
CS-T-60354 Phenol D5 4165-62-2 Stable Isotope Reagent
CS-BX-00365 Phenyl-D5-boronic acid 215527-70-1 Stable Isotopes
CS-BX-01153 Phenylacetic acid-α,α-d2 1076-07-9 Stable Isotopes
CS-O-02793 Piperazine-D8 Dihydrochloride 849482-21-9 Stable Isotope Reagent
CS-T-60800 Propionic Acid D3 55577-88-3 Stable Isotope Reagent
CS-R-00642 Propionic acid D5 60153-92-6 Stable Isotope Reagent
CS-T-85549 Propiophenone-d5 54419-23-7 Stable Isotopes
CS-O-15142 Sodium Deuteroxide 14014-06-3 Stable Isotope Reagent
CS-O-13174 Sulfuric Acid D2 13813-19-9 Stable Isotope Reagent
CS-C-00216 "Benzophenone-2,3,4,5,6-d5" 2694-78-2 Stable Isotopes
CS-CX-00453 "N,N-Dimethylaniline D6" 4019-61-8 Stable Isotopes
CS-T-53482 "1,1-Dimethyl-1-propanol D6" 75295-95-3 Stable Isotopes
CS-C-00175 "4-Bromoaniline-2,3,5,6-d4" 61357-76-4 Stable Isotopes
CS-T-59322 "4-Nitroaniline-2,3,5,6-D4" 64164-08-5 Stable Isotopes
CS-O-43154 (±)-1-Phenyl D5-Ethanol 90162-45-1 Stable Isotope Reagent
CS-O-43067 1-Bromo-4-iodo-2,3,5,6-tetradeuteriumbenzene 1147565-46-5 Stable Isotope Reagent
CS-O-42051 1-​(METHYL-​D3)​PIPERAZINE 2HCL 2043778-87-4 Stable Isotope Reagent
CS-T-94262 1,3-Dinitrobenzene-d4 54247-05-1 Stable Isotope Reagent
CS-T-49864 2-Bromopropane D6 52809-76-4 Stable Isotope Reagent
CS-T-49863 2-Bromopropane D7 39091-63-9 Stable Isotope Reagent
CS-C-00172 2-Methoxy-d3-benzaldehyde 56248-49-8 Stable Isotopes
CS-O-10078 2-Methylpropionic D7 Acid 223134-74-5 Stable Isotope Reagent
CS-O-42876 2-Phenylethan-1,1,2,2-d4-ol 107473-33-6 Stable Isotope Reagent
CS-O-42441 2-(METHOXY-D3)ANILINE 1398066-00-6 Stable Isotope Reagent
CS-T-67167 3-Bromoaniline D4 81395-17-7 Stable Isotopes
CS-T-67231 3-Bromonitrobenzene-d4 81395-16-6 Stable Isotopes
CS-O-39705 3-Chloro-2,4,5,6-tetradeuteroaniline 1027104-24-0 Stable Isotopes
CS-O-42469 3-(METHOXY-D3)ANILINE 1820607-08-3 Stable Isotope Reagent
CS-O-33121 4-amino-2,5,3,6-d4-phenol 70237-44-4 Stable Isotopes
CS-C-00162 4-Bromobenzoic-d4 Acid 787624-24-2 Stable Isotopes
CS-C-00199 4-Bromotoluene-2,3,5,6-d4 112484-85-2 Stable Isotope Reagent
CS-O-42491 4-(METHOXY-D3)ANILINE 1820684-56-7 Stable Isotope Reagent
CS-O-42492 4-(METHOXY-D3)BENZALDEHYDE 342611-04-5 Stable Isotope Reagent
CS-O-42292 4-[di(methyl-d3)amino]benzoic acid 1175002-09-1 Stable Isotope Reagent
CS-O-42300 5-bromo-1-(methyl-d3)-1H-indole 2140317-04-8 Stable Isotope Reagent