Chemical Properties of 'Cinacalcet Impurity E' |
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CAT No. : |
CS-O-07628 |
CAS Registry No. : | 253337-60-9 |
Category : | Impurity Standards |
Molecular Weight: | 339.90 |
Molecular Formula : | C₂₂H₂₆ClN |
OTHER INFORMATION of 'Cinacalcet Impurity E' |
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Purity : | >98% |
Purity : | >98% |
IUPAC Name : | 3-(3-methylphenyl)-N-[(1R)-1-naphthalen-1-ylethyl]propan-1-amine |
Applicationnotes : | Impurity in commercial preparations of Cinacalcet |
Synonym : | Not available |
References : | NULL |
Smileys : | C[C@H](C1=CC=CC2=CC=CC=C12)NCCCC3=CC(C)=CC=C3 |
Other Synonyms : | 253337-60-9 |
Removed Synonyms : | Cinacalcet Impurity E |
Exact Mass : | 303.198699802 |
InChI : | InChI=1S/C22H25N/c1-17-8-5-9-19(16-17)10-7-15-23-18(2)21-14-6-12-20-11-3-4-13-22(20)21/h3-6,8-9,11-14,16,18,23H,7,10,15H2,1-2H3/t18-/m1/s1 |
InchIKey : | BREGDWXNNPCUFR-GOSISDBHSA-N |
Canonical SMILES : | CC1=CC(=CC=C1)CCCNC(C)C2=CC=CC3=CC=CC=C32 |
Isomeric SMILES : | CC1=CC(=CC=C1)CCCN[C@H](C)C2=CC=CC3=CC=CC=C32 |
Custom Duty : | Applicable |
Port of Loading : | Canada |
Expected Dispatch : | 2-3 Weeks |
Taxes : | Not Applicable |
Refund Policy : | 30-days money back |
Custom Duty : | Applicable |
Port of Loading : | Canada |
Expected Dispatch : | 2-3 Weeks |
Taxes : | Not Applicable |
Refund Policy : | 30-days money back |
Cinacalcet, sold under the brand name Sensipar among others, is a medication used to treat tertiary hyperparathyroidism, parathyroid carcinoma, and primary hyperparathyroidism.
The most common side effects include nausea (feeling sick) and vomiting.
Cinacalcet acts as a calcimimetic (i.e., it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues.
Cinacalcet was approved in the United States in March 2004, and in the European Union in October 2004. It was the first allosteric G protein-coupled receptor modulator to enter the pharmaceutical market. In 2013, cinacalcet was the 76th top prescribed medicine in the United States.
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