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Ramipril EP Impurity E



Chemical Properties of 'Ramipril EP Impurity E'

CAT No. :

CS-O-08083
CAS Registry No. : 87269-97-4
Category : Metabolites
Molecular Weight: 388.46
Molecular Formula : C₂₁H₂₈N₂O₅



OTHER INFORMATION of 'Ramipril EP Impurity E'
Purity : Not less than 90 %
Therapeutic : Anti-Hypertensives
IUPAC Name :(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Applicationnotes :Impurity in commercial preparation of Ramipril.
Synonym :Ramiprilat
References :"Pilote L, Abrahamowicz M, Eisenberg M, Humphries K, Behlouli H, Tu JV (May 2008);Remuzzi, Giuseppe (April 2006)"
Smileys :O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(O)=O)CCC3=CC=CC=C3
Appearance :White to off white solid
EC Number :807-772-5
UNII :6N5U4QFC3G
NCI Thesaurus Code :C72911
RXCUI :1546377
MeSH Entry Terms :ramiprilat
Other Synonyms :Ramiprilat
Removed Synonyms :ramiprilat hydrate
Metabolite Pathways :Ramipril Action Pathway
Exact Mass :388.19982200
InChI :InChI=1S/C21H28N2O5/c1-13(22-16(20(25)26)11-10-14-6-3-2-4-7-14)19(24)23-17-9-5-8-15(17)12-18(23)21(27)28/h2-4,6-7,13,15-18,22H,5,8-12H2,1H3,(H,25,26)(H,27,28)/t13-,15-,16-,17-,18-/m0/s1
InchIKey :KEDYTOTWMPBSLG-HILJTLORSA-N
Canonical SMILES :CC(C(=O)N1C2CCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Isomeric SMILES :C[C@@H](C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(=O)O)N[C@@H](CCC3=CC=CC=C3)C(=O)O
Product Description :Ramiprilat is a dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a drug metabolite, a cardioprotective agent, a matrix metalloproteinase inhibitor and a bradykinin receptor B2 agonist. It is a cyclopentapyrrole, an azabicycloalkane, a dipeptide and a dicarboxylic acid.
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 17-Aug-2022
Taxes : Not Applicable
Refund Policy : 30-days money back
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 17-Aug-2022
Taxes : Not Applicable
Refund Policy : 30-days money back


More information about Ramipril


Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 years old to reduce the risk of having a heart attack, stroke or cardiovascular death in patients shown to be at high risk, such as some diabetics and patients with vascular disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth.

Common side effects include headaches, dizziness, feeling tired, and cough. Serious side effects may include liver problems, angioedema, kidney problems, and high blood potassium. Use in pregnancy and breastfeeding is not recommended. It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity.

Ramipril was patented in 1981 and approved for medical use in 1989. It is available as a generic medication. In 2019, it was the 178th most commonly prescribed medication in the United States, with more than 3\u00a0million prescriptions.





This page contains information about Ramipril EP Impurity E , Ramipril EP Impurity E cas, Ramipril EP Impurity E synthesis, Ramipril EP Impurity E suppliers

What is Ramipril EP Impurity E ?
Ramipril EP Impurity E falls under Metabolites of Ramipril.Impurity in commercial preparation of Ramipril.
What is the CAS Number of Ramipril EP Impurity E?
The CAS Number of Ramipril EP Impurity E is 87269-97-4
Who are the suppliers of Ramipril EP Impurity E?
CLEARSYNTH is a worldwide supplier of Ramipril EP Impurity E

List of Ramipril Metabolites

Related compounds of Ramipril EP Impurity E

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