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Torsemide



Chemical Properties of 'Torsemide'

CAT No. :

CS-O-11763
CAS Registry No. : 56211-40-6
Category : API Standards
Molecular Weight: 348.42
Molecular Formula : C₁₆H₂₀N₄O₃S



OTHER INFORMATION of 'Torsemide'
Purity : Not less than 95%
Purity : Not less than 95%
IUPAC Name :1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea
Synonym :Not available
References :"Lesne; M,; et al,: In, J, Clin, Pharmacol, Ther, Toxicol,; 20; 382 (1982); Brater; D,C,; et al,: Clin, Pharmacol, Ther,; 42; 187 (1987);"
Appearance :White to off white solid
Melting Point :163-164 °C
Solubility :>52.3 [ug/mL]
Use Classification :Veterinary drugs -> UpCard -> EMA Drug Category
Hazard Class :Eye Irrit. 2 (88.57%)
EC Number :637-197-3
UNII :W31X2H97FB
NCI Thesaurus Code :C29506
RXCUI :38413
MeSH Entry Terms :1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
Other Synonyms :Torasemide
Removed Synonyms :Presoril
Label Ingredient : TORSEMIDE
NDC Code :0004-0262-01, 0004-0262-49, 0004-0263-01, 0004-0263-49, 0004-0264-01, 0004-0264-49, 0004-0265-01, 0004-0265-49, 0004-0267-06, 0004-0268-06 ... total 99.
Metabolite Pathways :Torsemide Action Pathway
Toxicity Summary :The oral LD50 of torasemide in the rat is 5 g/kg. When overdose occurs, there is a marked diuresis with the danger of loss of fluid and electrolytes which has been seen to lead to somnolence, confusion, hypotension, hyponatremia, hypokalemia, hypochloremic alkalosis, hemoconcentration dehydration and circulatory collapse. This effects can include some gastrointestinal disturbances. There is no increase in tumor incidence with torasemide and it is proven to not be mutagenic, not fetotoxic or teratogenic.
Drug Induced Liver Injury :torasemide
Protein Binding :Torasemide is found to be highly bound to plasma proteins, representing over 99% of the administered dose.
Exact Mass :348.12561169
InChI :InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
InchIKey :NGBFQHCMQULJNZ-UHFFFAOYSA-N
Canonical SMILES :CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C
Isomeric SMILES :CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C
Product Description :Torasemide is an N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure. It has a role as a loop diuretic and an antihypertensive agent. It is a N-sulfonylurea, an aminopyridine and a secondary amino compound. It derives from a 4-aminopyridine.
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back


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This page contains information about Torsemide , Torsemide cas, Torsemide synthesis, Torsemide suppliers

What is Torsemide ?
Torsemide falls under API Standards of Torsemide.
What is the CAS Number of Torsemide?
The CAS Number of Torsemide is 56211-40-6
Who are the suppliers of Torsemide?
CLEARSYNTH is a worldwide supplier of Torsemide

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