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(1S,2R) Bortezomib

ISO 17034:
Catalog Number : CS-O-20087
CAS Number : 1132709-16-0
Status : Available for immediate dispatch
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Chemical Information

Chemical Name : (1S,2R) Bortezomib
Category : Chiral
Purity : Not less than 95 %
Synonyms : Not available
Molecular Weight : 384.24 mol/g
Molecular Formula : C₁₉H₂₅BN₄O₄
Application : "(1S,3R)-Bortezomib is an diastereomer of Bortezomib , the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus"
Therapeutic : Synthetic Peptides

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Hazardous Compound : No

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Taxes : All prices are inclusive taxes
Refund Policy : 30 days money back guarantee

Additional Information

Medical use

References : "Nawrcki, S,T,, et al:cacer Reseach, 65, 11510 (2005); Drahlc,:chem, and Eng, News, 87, 41 (2009)"
Canonical SMILES : B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
Isomeric SMILES : B([C@@H](CC(C)C)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
InChI : InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m1/s1
IUPAC Name : [(1S)-3-methyl-1-[[(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
Exact Mass : 384.1968855

Related compounds of (1S,2R) Bortezomib

CS-O-31035 Bortezomib 1R, 2R Isomer 1132709-15-9 Chiral
CS-O-20088 (1S,2S) Bortezomib 1132709-14-8 Chiral