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Tacrolimus

ISO 17034:
Catalog Number : CS-O-30787
CAS Number : 104987-11-3
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What is the Chemical Information of Tacrolimus?

Chemical Name : Tacrolimus
Category : API Standards
Purity : Not less than 90%
Molecular Weight : 804.02 mol/g
Molecular Formula : C₄₄H₆₉NO₁₂
Application : A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Therapeutic : Immunosuppressants

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References : "Asano, K,, et al,: In Vivo, 10, 537 (1996), McCall, E,, et al,: Circ, Res,, 79, 1110 (1996), Raufman, J,P,, et al,: J, Biol, Chem,, 271, 19877 (1996), Rokaw, M,D,, et al,: Am, J, Physiol,, 271, C194 (1996), Knoll, G,A,, and Bell, R,C,: Brit, Med, J,, 318,|???|???????"