OTHER INFORMATION
of 'Acetamide'
|
| Therapeutic : |
Antiretroviral / Anti-HIV |
| Therapeutic : |
Antiretroviral / Anti-HIV |
| IUPAC Name : | acetamide |
| Chemical name of this compound, computed from its structure based on the International Union of Pure and Applied Chemistry (IUPAC) nomenclature standards. |
| Synonym : | Daclatasvir Impurity-S |
| Related CAS : |
74330-92-0 |
| The Chemical Abstract Service (CAS) registry numbers for related chemicals (e.g., parents, components, mixtures, salt forms, etc.) |
| Color / Form : | Deliquescent hexagonal crystals |
| Color is the aspect of any object that may be described in terms of hue, lightness, and saturation. |
| ODOR : | Odorless when pure, but frequently has a mousy odor |
| Melting Point : | 180.1 °F (NTP, 1992) |
| Boiling Point : | 430 °F at 760 mm Hg (NTP, 1992) |
| Solubility : | Very soluble (greater than or equal to 100 mg/mL at 72° F) (NTP, 1992) |
| Density : | 1.159 at 68 °F (NTP, 1992) |
| Chemical Classes : | Nitrogen Compounds -> Other Nitrogen Compounds |
| Use Classification : | Hazardous Air Pollutants (HAPs) |
| This section contains use classification/category information for this compound from various sources. |
| Hazard Class : | Carc. 2 |
| The Hazard Classes and Categories are aligned with GHS (Globally Harmonized System of Classification and Labelling of Chemicals) hazard statement codes. |
| EC Number : | 200-473-5 |
| The European Community (EC) number is a seven-digit identifier assigned by the European Chemicals Agency (ECHA) to substances for regulatory purposes within the European Union. EC numbers are sometimes referred to as EINECS, ELINCS, or NLP numbers |
| UNII : | 8XOE1JSO29 |
| UNique Ingredient Identifier (UNII) code for this chemical. It is a non-proprietary registry number assigned by the U.S. Food and Drug Administration (FDA). |
| MeSH Entry Terms : | acetamide |
| Medical Subject Heading (MeSH) names or identifiers matching this PubChem Compound record. The matching between the MeSH and compound records is performed by name matching (i.e., identical common names) |
| Other Synonyms : | acetamide |
| Removed Synonyms : | Methylformamide |
| Vapor Pressure : |
1 mm Hg at 149 °F (NTP, 1992) |
| Vapor pressure (or equilibrium vapor pressure) is the pressure of a vapor in thermodynamic equilibrium with its condensed phases in a closed system. |
| Other Experimental Properties : | Acetamide may react with azo and diazo compounds to generate toxic gases. May form flammable gases with strong reducing agents. Reacts as a weak base (weaker than water). |
| Disposal Methods : | SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. |
| Disposal methods or procedures for this chemical or hazardous waste containing it. |
| Toxicity Summary : | IDENTIFICATION AND USE: Acetamide is a solid. It is used as a solvent and stabilizer, accelerator in the estimation of bilirubin, antidote against monofluoroacetamide poisoning, and humectant for paper. HUMAN EXPOSURE AND TOXICITY: There are no data available. ANIMAL STUDIES: When acetamide was administered at a concentration of 5% in the diet to 99 male rats, with 2 rats returned to a control diet each week, liver tumors were found after treatment for 14-40 weeks in 22/81 rats. Acetamide-treated rats developed neoplastic nodules and hepatocellular carcinomas. The incidence, speed of onset, and frequency of metastases were greater in males than in females. Acetamide had the least toxic effects in regards to teratogenicity and embryotoxicity, compared to its derivatives. Acetamide produced morphological transformation in Syrian hamster embryo cells without metabolic activation. ECOTOXICITY STUDIES: Acetamide exhibited a selective damaging action on Entosiphon sulcatum. |
| Summary of the toxicity of this compound, provided by the Hazardous Substances Data Bank (HSDB). |
| Interactions : | Two groups of 40 male wistar rats were fed diets containing 2.5% acetamide or 2.5% acetamide + 5.6 l-arginine, & 2 groups of 15 males were fed diet containing 5.6% arginine glutamate or a control diet for 1 yr. In 2/8 rats fed acetamide ... hepatomas ... were observed; 7/16 rats fed acetamide for 1 yr and maintained on control diet for further 3 MO developed liver tumors. In contrast, 1/11 rats that received acetamide + arginine glutamate for 1 yr and control diet for 3 MO had hyperplastic liver nodules. No liver tumors occurred in control group nor in rats fed 5.6% arginine glutamate alone. |
| Interactions of this compound with other chemicals, according to the Hazardous Substances Data Bank (HSDB). |
| Antidoteand Emergency Treatment : | If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 min, occasionally lifting upper and lower lids. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. When this chemical has been swallowed, get medical attention. ... If this chemical has been inhaled, remove from exposure and transfer promptly to a medical facility. |
| Information on antidote and emergency treatment when exposed to this chemical. The information here is from the Hazardous Substances Data Bank (HSDB). |
| Non Human Toxicity Excerpts : | /LABORATORY ANIMALS: Acute Exposure/ Max tolerated single dose for male rats and ... mice are 7.5 and 8 g/kg body wt, and corresponding LD50 values are 10.3 and 10.1 g/kg body wt (observed after 24 hr). |
| Excerpts about non-human toxicity of this compound, extracted from authoritative documents, such as journal articles, government reports, and reference books. |
| Exact Mass : | 59.037113783 |
| The exact mass of an isotopic species is obtained by summing the masses of the individual isotopes of the molecule. |
| InChI : | InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4) |
| The International Chemical Identifier (InChI) is a computed, non-proprietary identifier for a chemical structure. The InChI is an International Union of Pure and Applied Chemistry (IUPAC) standard. |
| InchIKey : | DLFVBJFMPXGRIB-UHFFFAOYSA-N |
| An InChIKey is a 27-character hash code derived from an InChI. The International Chemical Identifier (InChI) is a computed, non-proprietary identifier for a chemical structure. |
| Canonical SMILES : | CC(=O)N |
| The Simplified Molecular-Input Line-Entry System (SMILES) is a widely-used line notation for chemical structures. |
| Isomeric SMILES : | CC(=O)N |
| The Simplified Molecular-Input Line-Entry System (SMILES) is a widely-used line notation for chemical structures. |
| Hazard Summary : | Acetamide is used primarily as a solvent and a plasticizer. Workers may be exposed in the plastics and chemical industries. It causes mild skin irritation from acute (short-term) exposure. No information is available on the chronic (long-term), reproductive/developmental, or carcinogenic effects of acetamide in humans. EPA has not classified acetamide for carcinogenicity. |
| Product Description : | Acetamide is a member of the class of acetamides that results from the formal condensation of acetic acid with ammonia. It is a monocarboxylic acid amide, a N-acylammonia and a member of acetamides. It is a tautomer of an acetimidic acid. |
| Custom Duty : |
Applicable |
| Port of Loading : |
Canada |
| Expected Dispatch : |
15-Aug-2022 |
| Taxes : |
Not Applicable |
| Refund Policy : |
30-days money back |
| Custom Duty : |
Applicable |
| Port of Loading : |
Canada |
| Expected Dispatch : |
15-Aug-2022 |
| Taxes : |
Not Applicable |
| Refund Policy : |
30-days money back |
