OTHER INFORMATION
of 'N-Nitrosoethylmethylamine'
|
| IUPAC Name : | N-ethyl-N-methylnitrous amide |
| Chemical name of this compound, computed from its structure based on the International Union of Pure and Applied Chemistry (IUPAC) nomenclature standards. |
| Synonym : | Not available |
| Color / Form : | Yellow liquid |
| Color is the aspect of any object that may be described in terms of hue, lightness, and saturation. |
| Melting Point : | Vapor pressure |
| Boiling Point : | 170.0 °C |
| Solubility : | 3.40 M |
| Density : | 0.9448 at 18 °C/4 °C |
| Chemical Classes : | Nitrogen Compounds -> Nitrosamines |
| Use Classification : | Health Hazards -> Carcinogens |
| This section contains use classification/category information for this compound from various sources. |
| Hazard Class : | Acute Tox. 3 (100%) |
| The Hazard Classes and Categories are aligned with GHS (Globally Harmonized System of Classification and Labelling of Chemicals) hazard statement codes. |
| EC Number : | 621-991-1 |
| The European Community (EC) number is a seven-digit identifier assigned by the European Chemicals Agency (ECHA) to substances for regulatory purposes within the European Union. EC numbers are sometimes referred to as EINECS, ELINCS, or NLP numbers |
| UNII : | 00RLM29Y3A |
| UNique Ingredient Identifier (UNII) code for this chemical. It is a non-proprietary registry number assigned by the U.S. Food and Drug Administration (FDA). |
| MeSH Entry Terms : | ethylmethylnitrosamine |
| Medical Subject Heading (MeSH) names or identifiers matching this PubChem Compound record. The matching between the MeSH and compound records is performed by name matching (i.e., identical common names) |
| Other Synonyms : | N-NITROSOMETHYLETHYLAMINE |
| Removed Synonyms : | Nema |
| Vapor Pressure : |
1.1 [mmHg] |
| Vapor pressure (or equilibrium vapor pressure) is the pressure of a vapor in thermodynamic equilibrium with its condensed phases in a closed system. |
| Other Experimental Properties : | Hydroxyl radical reaction rate constant = 1.0X10-11 cu cm/molecule-sec at 25 °C (est) |
| Disposal Methods : | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations. |
| Disposal methods or procedures for this chemical or hazardous waste containing it. |
| Antidoteand Emergency Treatment : | Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Organic bases/Amines and related compounds/ |
| Information on antidote and emergency treatment when exposed to this chemical. The information here is from the Hazardous Substances Data Bank (HSDB). |
| Human Toxicity Excerpts : | /GENOTOXICITY/ The role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines was examined by Ames test using genetically engineered Salmonella typhimurium (S. typhimurium)YG7108 cells expressing each form of human CYP together with human NADPH-cytochrome P450 reductase (OR). The relationship between the structure of N-alkylnitrosamines and CYP form(s) involved in the activation was evaluated. Eleven strains of S. typhimurium YG7108 cells expressing each form of CYP (CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4 or CYP3A5) were employed. Eight N-alkylnitrosamines including ... N-nitrosomethylethylamine (NMEA) ... were examined. ... N-alkylnitrosamines with relatively short alkyl chains such as ... NMEA were primarily activated by CYP2E1 as judged by mutagen-producing capacity. ... |
| Excerpts about human toxicity of this compound, extracted from authoritative documents, such as journal articles, government reports, and reference books. |
| Non Human Toxicity Excerpts : | /LABORATORY ANIMALS: Chronic Exposure or Carcinogenicity/ A group of 15 female BD rats was given N-nitrosomethylethylamine (NMEA) in the drinking-water at doses of 1 or 2 mg/kg bw per day. Nine of 15 animals developed hepatocellular carcinomas, and one animal a fibrosarcoma of the vagina. The average induction time was 500 or 360 days, respectively; the average total dose to induce tumors in 50% of animals was 0.42 or 0.75 g/kg bw, respectively. |
| Excerpts about non-human toxicity of this compound, extracted from authoritative documents, such as journal articles, government reports, and reference books. |
| Exact Mass : | 88.063662883 |
| The exact mass of an isotopic species is obtained by summing the masses of the individual isotopes of the molecule. |
| InChI : | InChI=1S/C3H8N2O/c1-3-5(2)4-6/h3H2,1-2H3 |
| The International Chemical Identifier (InChI) is a computed, non-proprietary identifier for a chemical structure. The InChI is an International Union of Pure and Applied Chemistry (IUPAC) standard. |
| InchIKey : | RTDCJKARQCRONF-UHFFFAOYSA-N |
| An InChIKey is a 27-character hash code derived from an InChI. The International Chemical Identifier (InChI) is a computed, non-proprietary identifier for a chemical structure. |
| Canonical SMILES : | CCN(C)N=O |
| The Simplified Molecular-Input Line-Entry System (SMILES) is a widely-used line notation for chemical structures. |
| Isomeric SMILES : | CCN(C)N=O |
| The Simplified Molecular-Input Line-Entry System (SMILES) is a widely-used line notation for chemical structures. |
| Hazard Summary : | Danger of cutaneous absorption; MAC-2 (considered to be carcinogenic for man because sufficient data from long-term animal studies or limited evidence from animal studies substantiated by evidence from epidemiological studies indicate that it can make a significant contribution to cancer risk); [MAK] An irritant; Causes liver injury in high-dose animal studies; [MSDSonline] |
| Product Description : | N-Nitrosomethylethylamine is a nitroso compound. |
| Custom Duty : |
Applicable |
| Port of Loading : |
Canada |
| Expected Dispatch : |
2-3 Weeks |
| Taxes : |
Not Applicable |
| Refund Policy : |
30-days money back |
| Custom Duty : |
Applicable |
| Port of Loading : |
Canada |
| Expected Dispatch : |
2-3 Weeks |
| Taxes : |
Not Applicable |
| Refund Policy : |
30-days money back |
