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Metyrosine D3



Chemical Properties of 'Metyrosine D3'

CAT No. :

CS-T-93581
CAS Registry No. : 672-87-7 (Unlabeled)
Category : Isotope Labelled Compounds
Molecular Weight: 198.23
Molecular Formula : C₁₀H₁₀D₃NO₃



OTHER INFORMATION of 'Metyrosine D3'
IUPAC Name :(2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
Synonym :Metyrosine-D3; (S)-2-(4-Hydroxybenzyl)-2-aminopropanoic Acid-D3; (S)-α-Methyltyrosine-D3; Demser-D3; L(-)-Metyrosine-D3; L-Metyrosine-D3; L-α-MT-D3; L-α-Methyl-p-tyrosine-D3; L-α-Methyltyrosine-D3; MK 781-D3; Metirosine-D3
Smileys :O=C(O)[C@@](N)(CC1=CC=C(O)C=C1)C([2H])([2H])[2H]
Solubility :Very slightly soluble
Use Classification :Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
EC Number :211-599-5
UNII :DOQ0J0TPF7
NCI Thesaurus Code :C998
RXCUI :266604
MeSH Entry Terms :alpha Methyl p tyrosine
Other Synonyms :METYROSINE
Removed Synonyms :Racemetirosine
Label Ingredient : METYROSINE
NDC Code :25010-305-15, 60219-1621-1, 68682-310-01, 69238-1621-1, 69238-1621-3
Toxicity Summary :Signs of metyrosine overdosage include those central nervous system effects observed in some patients even at low dosages. At doses exceeding 2000 mg/day, some degree of sedation or feeling of fatigue may persist. Doses of 2000-4000 mg/day can result in anxiety or agitated depression, neuromuscular effects (including fine tremor of the hands, gross tremor of the trunk, tightening of the jaw with trismus), diarrhea, and decreased salivation with dry mouth. The acute toxicity of metyrosine was 442 mg/kg and 752 mg/kg in the female mouse and rat respectively.
Drug Induced Liver Injury :metyrosine
Exact Mass :195.08954328
InChI :InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1
InchIKey :NHTGHBARYWONDQ-JTQLQIEISA-N
Canonical SMILES :CC(CC1=CC=C(C=C1)O)(C(=O)O)N
Isomeric SMILES :C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N
Product Description :Alpha-methyl-L-tyrosine is an L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It has a role as an antihypertensive agent and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. It is a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid.
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back
Custom Duty : Applicable
Port of Loading : Canada
Expected Dispatch : 2-3 Weeks
Taxes : Not Applicable
Refund Policy : 30-days money back


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