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6a,9a-Difluoroprednisolone-17-butyrate-d6, also known as DFBA-d6, is a deuterated derivative of the synthetic glucocorticoid 6α,9α-difluoroprednisolone-17-butyrate. DFBA-d6 is a stable isotope-labeled compound that is used primarily as an internal standard in mass spectrometry-based analytical methods for the quantitative determination of 6α,9α-difluoroprednisolone-17-butyrate in biological samples.
The chemical formula for DFBA-d6 is C27H31D6F2O7, and its molecular weight is 545.60 g/mol. The compound is a white to off-white powder that is slightly soluble in water and soluble in organic solvents, such as methanol, ethanol, and acetone.
DFBA-d6 is typically used in pharmacokinetic and bioavailability studies of 6α,9α-difluoroprednisolone-17-butyrate, a potent glucocorticoid with anti-inflammatory and immunosuppressive properties. This synthetic steroid is used in the treatment of various inflammatory and autoimmune disorders, such as rheumatoid arthritis, asthma, and inflammatory bowel disease.
In conclusion, 6a,9a-Difluoroprednisolone-17-butyrate-d6 is a deuterated derivative of a synthetic glucocorticoid used as an internal standard in mass spectrometry-based analytical methods for the quantitative determination of 6α,9α-difluoroprednisolone-17-butyrate in biological samples. The compound is used in pharmacokinetic and bioavailability studies of the parent compound, a potent glucocorticoid used in the treatment of various inflammatory and autoimmune disorders.
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