[13C5]-5'-Deoxy-5-fluorocytidine

[13C5]-5'-Deoxy-5-fluorocytidine is a modified form of the nucleoside analog 5'-Deoxy-5-fluorocytidine, which is used as an antiviral agent against hepatitis B and C viruses. The addition of five carbon-13 isotopes to the structure of the molecule allows for more precise analysis and tracking of the compound in biological systems. The chemical formula of [13C5]-5'-Deoxy-5-fluorocytidine is C9H11FN3O4 and it has a molecular weight of 253.20 g/mol. The molecule works by inhibiting the viral enzyme, RNA-dependent DNA polymerase, which is essential for the replication of hepatitis viruses. This inhibition leads to the interruption of viral replication and ultimately reduces the viral load in infected individuals. [13C5]-5'-Deoxy-5-fluorocytidine is typically administered orally in the form of tablets or capsules. It is rapidly absorbed in the gastrointestinal tract and is metabolized in the liver to its active form, 5'-triphosphate, which is responsible for its antiviral activity. The use of [13C5]-5'-Deoxy-5-fluorocytidine is associated with some side effects, including gastrointestinal disturbances, fatigue, and headaches. It is important to monitor liver function in patients receiving this medication, as it can cause liver damage in rare cases. Overall, [13C5]-5'-Deoxy-5-fluorocytidine is a valuable antiviral agent in the treatment of hepatitis B and C viruses. Its modification with carbon-13 isotopes improves its analysis and tracking in biological systems, making it a useful tool for research and development in the field of antiviral therapy.