Ezetimibe Didesfluro impurity

Product Name Ezetimibe Didesfluro impurity
Alternate Names Ezetimibe Impurities, Impurities of Ezetimibe
CAT No. CS-T-15984
CAS No. 302781-98-2
Category Impurities
Stock IN-Stock
Mol. Wt. 391.43 g/mol
Mol. For. C₂₄H₂₂FNO₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ezetimibe
Therapeutic Anti-Hyperlipidemics
Smileys O[C@H](C1=CC=C(F)C=C1)CC[C@@H]2[C@@H](C3=CC=C(O)C=C3)N(C4=CC=CC=C4)C2=O
Canonical Smiles C1=CC=C(C=C1)N2C(C(C2=O)CCC(C3=CC=C(C=C3)F)O)C4=CC=C(C=C4)O
InchIKey YWZUFJFIXFJKBD-XPWALMASSA-N
Inchl InChI=1S/C24H22FNO3/c25-18-10-6-16(7-11-18)22(28)15-14-21-23(17-8-12-20(27)13-9-17)26(24(21)29)19-4-2-1-3-5-19/h1-13,21-23,27-28H,14-15H2/t21-,22+,23-/m1/s1
IUPAC (3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
Controlled No
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Ezetimibe is a medication used to lower blood cholesterol levels by reducing the absorption of cholesterol in the intestine. However, during the synthesis of Ezetimibe, a byproduct called Ezetimibe Didesfluro Impurity is formed, which needs to be removed from the final product. Ezetimibe Didesfluro Impurity, also known as 2-Amino-2-methyl-1-propanol-1,3-difluoro-4-(4-fluorophenyl)-5-oxo-1,5-dihydro-4H-pyrazolo[3,4-d]pyridazin-6-olate, is a chemical compound that is classified as an impurity. It is formed during the process of synthesis of Ezetimibe, and it is essential to remove it from the final product as it can affect the efficacy of the medication. Chemically, Ezetimibe Didesfluro Impurity contains a pyrazolopyridazine ring system, which is characteristic of the Ezetimibe molecule. However, it also contains a difluoro group and a fluoro group, which are not present in the parent compound. These additional groups can cause changes in the physical and chemical properties of the compound, which can affect its pharmacological activity. In conclusion, Ezetimibe Didesfluro Impurity is an unwanted byproduct formed during the synthesis of Ezetimibe. It is essential to remove this impurity from the final product to ensure the efficacy and safety of the medication.

Related Compounds

Methyl 5-(4-Fluorophenyl)-(5S)-hydroxypentanoate | Benzyl Ezetimibe ether | Ezetimibe (3S,4S,3'R)-Isomer | m-Fluoroaniline isomer of Ezetimibe | Ezetimibe Impurity B | Ezetimibe Related Impurity 7 | Ezetimibe Trihydroxy Impurity | Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | Ezetimibe Desfluoro impurity | O-Fluoroaniline isomer of Ezetimibe | Ezetimibe 2-Fluoro impurity | Ezetimibe Lactone Impurity | SSR-Ezetimibe | RRR-Ezetimibe+SSS-Ezetimibe (Diastereomer mixture) | Ezetimibe Impurity 17 | Benzylated Ezetimibe | Ezetimibe Diacid | Ezetimibe Impurity 11 | Ezetimibe Deprotected Impurity | Ezetimibe Dides fluoro impurity | N-Nitroso Ezetimibe Impurity | Ezetimibe Azetidinone Ring opened impurity | ent-Ezetimibe | Ezetimibe 2-Fluoro Hydroxy impurity | Ezetimibe Benzyl Impurity (MBZT-2) | Ezetimibe Impurity C | Ezetimibe Impurity 1 ((3'S,3R,4S)-Desfluoro Ezetimibe) | Ezetimibe Impurity 10 | Ezetimibe ring open impurity | Ezetimibe Ring-opening Dehydrate Impurity | Ezetimibe Impurity 18 | Ezetimibe (3R,4R,3'R)-Isomer | O-Fluorobenzene isomer of Ezetimibe | Ezetimibe Triol Impurity | Ezetimibe tetrahydropyran analog | Ezetimibe Diol Impurity | RSR Ezetimibe | Ezetimibe Benzyl Diol Impurity | Ezetimibe Impurity 25 | Ezetimibe Lactam Cleaved Alcohol | Ezetimibe Impurity 15 | Ezetimibe O-trimethylsilyl O-benzyl Impurity |

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