ent-Ezetimibe

Product Name ent-Ezetimibe
Alternate Names Ezetimibe Impurities, Impurities of Ezetimibe
CAT No. CS-T-75143
CAS No. 1376614-99-1
Category Impurities
Stock IN-Stock
Mol. Wt. 409.43 g/mol
Mol. For. C₂₄H₂₁F₂NO₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ezetimibe
Purity Not less than 90 %
Therapeutic Anti-Hyperlipidemics
Smileys O[C@@H](C1=CC=C(F)C=C1)CC[C@H]2[C@H](C3=CC=C(O)C=C3)N(C4=CC=C(F)C=C4)C2=O
Canonical Smiles C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
InchIKey OLNTVTPDXPETLC-ZRBLBEILSA-N
Inchl InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m0/s1
IUPAC (3S,4R)-1-(4-fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Controlled No
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Ent-Ezetimibe is a medication used to lower cholesterol levels in the body. It belongs to a class of drugs known as cholesterol absorption inhibitors. The drug works by blocking the absorption of cholesterol from the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. Ent-Ezetimibe is a stereoisomer of the commonly used medication Ezetimibe. It has the same chemical formula and structure as Ezetimibe, but the orientation of the atoms in the molecule is different. This difference in orientation gives ent-Ezetimibe slightly different pharmacological properties than Ezetimibe. The chemical name for ent-Ezetimibe is (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one. The molecular formula is C24H21F2NO3 and the molecular weight is 409.4 g/mol. Ent-Ezetimibe is typically administered orally as a tablet. The recommended dose is 10 mg once daily, with or without food. The drug is metabolized in the liver and excreted in the feces. Overall, ent-Ezetimibe is a safe and effective medication for reducing cholesterol levels in the body. It is important to note that ent-Ezetimibe should not be used as a substitute for a healthy diet and exercise. It is best to consult with a healthcare provider to determine if ent-Ezetimibe is right for you.

Related Compounds

Benzylated Ezetimibe | Ezetimibe tetrahydropyran analog | Ezetimibe Related Impurity 7 | Ezetimibe Ring-opening Dehydrate Impurity | Ezetimibe Diacid | Ezetimibe Desfluoro impurity | Ezetimibe Impurity 18 | Ezetimibe Impurity C | Ezetimibe Lactone Impurity | Ezetimibe Impurity 10 | Ezetimibe Impurity 11 | Ezetimibe Impurity 25 | O-Fluorobenzene isomer of Ezetimibe | Ezetimibe Impurity 17 | Ezetimibe 2-Fluoro impurity | Ezetimibe (3R,4R,3'R)-Isomer | Ezetimibe Azetidinone Ring opened impurity | Ezetimibe Impurity 15 | Ezetimibe (3S,4S,3'R)-Isomer | RRR-Ezetimibe+SSS-Ezetimibe (Diastereomer mixture) | RSR Ezetimibe | Ezetimibe Lactam Cleaved Alcohol | Ezetimibe Impurity 1 ((3'S,3R,4S)-Desfluoro Ezetimibe) | Ezetimibe Didesfluro impurity | Benzyl Ezetimibe ether | Ezetimibe Trihydroxy Impurity | Ezetimibe Triol Impurity | Ezetimibe Impurity B | m-Fluoroaniline isomer of Ezetimibe | O-Fluoroaniline isomer of Ezetimibe | Ezetimibe O-trimethylsilyl O-benzyl Impurity | Ezetimibe Diol Impurity | Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | Ezetimibe Deprotected Impurity | Ezetimibe ring open impurity | Ezetimibe Benzyl Impurity (MBZT-2) | Ezetimibe 2-Fluoro Hydroxy impurity | Ezetimibe Dides fluoro impurity | N-Nitroso Ezetimibe Impurity | Ezetimibe Benzyl Diol Impurity | Methyl 5-(4-Fluorophenyl)-(5S)-hydroxypentanoate | SSR-Ezetimibe |

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